Background & Objective: To identify patient's factors from their clinical picture and demographics, and recognize their association and influence on frequency of physician visit.
Method: Study was conducted in Karachi from January - December 2019. Primary data was collected from 255 asthmatic patients that visited different hospitals, homeopathic and herbal clinics. Questionnaire included patient's demographic details, treatment choice for asthma and satisfaction level with different treatments. Collected data was analyzed by SPSS 20.
Result: Among 255 asthmatic patients, 101 visited 5 - 7 times to physician from the past year, 48 visited 8-10 times and 27 went to physician more than 10 times in past 12 months. While 30 patients did not visit the physician even once and only 20 patients visited 1-2 times in the last year. From clinical factors, association of severity (p = 0.0001), limitation (p = 0.0001) and side effects (p = 0.003) with physician visit were found to be statistically significant. In addition, among demographics, age (p = 0.004), education (p = 0.0001), income (p = 0.0001) and having pets (p = 0.007) were found to be significant factors associated with physician visit for asthma in the past year.
Conclusion: Most of the asthmatic patients covered in the study visited the physician more than five times during the last year and chose allopathic treatment for asthma. Age, education, severity and side effects of asthma treatment were some of the significant factors associated with physician visit. Patients with frequent follow up visits to the physician were satisfied with their treatment.
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http://dx.doi.org/10.1016/j.jsps.2021.01.003 | DOI Listing |
J Infect Dev Ctries
December 2024
Family Medicine, Merkezefendi District Health Directorate, Denizli, Turkey.
Introduction: Post-COVID-19 syndrome refers to the occurrence of symptoms lasting more than 4 weeks in individuals who have recovered from COVID-19. This study aims to investigate the post-COVID-19 symptoms in healthcare professionals.
Methodology: This descriptive study included 166 healthcare professionals who had tested positive for COVID-19 via PCR at least four weeks prior and subsequently presented to the Family Medicine Clinic at Pamukkale University Training and Research Hospital.
J Asthma Allergy
January 2025
Amgen Inc., Thousand Oaks, CA, USA.
Airway inflammation, a hallmark feature of asthma, drives many canonical features of the disease, including airflow limitation, mucus plugging, airway remodeling, and hyperresponsiveness. The T2 inflammatory paradigm is firmly established as the dominant mechanism of asthma pathogenesis, largely due to the success of inhaled corticosteroids and biologic therapies targeting components of the T2 pathway, including IL-4, IL-5, IL-13, and thymic stromal lymphopoietin (TSLP). However, up to 30% of patients may lack signatures of meaningful T2 inflammation (ie, T2 low).
View Article and Find Full Text PDFFront Pharmacol
January 2025
Phase I Clinical Trial Site, Nanjing Gaoxin Hospital, Nanjing, Jiangsu, China.
Background: Fluticasone propionate is a synthetic trifluoro-substituted glucocorticoid, a highly selective glucocorticoid receptor agonist. Fluticasone propionate nebuliser suspensions is an inhaled corticosteroid with the low systemic bioavailability which provides a low risk (benefit outcome without the adverse effects that accompany systemically administered corticosteroids), referred as a first-line preventive agent for patients with persistent asthma. China has become one of the countries with the highest asthma mortality rate in the world in the past years.
View Article and Find Full Text PDFWorld Allergy Organ J
January 2025
Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy.
Background: This study aimed to evaluate the impact of severe asthma (SA) treatments after 12 months in achieving clinical remission (CR) within the context of the Severe Asthma Network in Italy (SANI) using the recent SANI definition of CR on treatment.
Methods: CR has been defined by SANI as complete, partial, and no CR. Complete CR is defined by the absence of oral corticosteroids (OCS), no symptoms, no exacerbations, and stable lung function, and partial CR requires the absence of OCS and the fulfillment of 2 out of the other 3 criteria.
Allergy
January 2025
School of Immunology and Microbial Sciences, King's College London, London, UK.
Background: Alarmin cytokine IL-25 promotes type 2 inflammatory responses in disorders such as asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and known targets include ILC2 and Th2 cells. However, other cellular targets for IL-25 remain poorly defined.
Objective: To investigate induction and expression of IL-25 receptor (IL-17RB) by B cells and evaluate responsiveness of IL-17RB-expressing B cells to IL-25 in vitro.
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