AI Article Synopsis
- - Linezolid is commonly used to treat chronic infections, especially in prosthetic joint cases, but its long-term use carries risks of serious side effects.
- - A case is presented where a patient experienced linezolid toxicity, resulting in bone marrow suppression, lactic acidosis, and drug-induced liver damage.
- - The case underscores the heightened risk of acute multiorgan failure for patients on prolonged linezolid treatment, particularly those with existing health issues.
Article Abstract
Linezolid is a frequently prescribed antibiotic for chronic infection suppression, such as in prosthetic joint infections. While well tolerated, its prolonged use can increase the risk of rare and serious side effects. We present a case of linezolid toxicity presenting with a constellation of adverse effects including bone marrow suppression, lactic acidosis, and drug-induced liver injury. Our case highlights the increased risk of acute multiorgan failure in patients using the antibiotic for extended durations, notably those with preexisting comorbidities.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901438 | PMC |
| http://dx.doi.org/10.1080/08998280.2020.1855922 | DOI Listing |
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