Objectives: School-based interventions can establish positive behaviours that reduce the likelihood of oral diseases later in life. The Brush Day & Night (BDN) programme is a 21-day school-based educational programme to promote good oral health behaviours. This study aims to evaluate the effect of the BDN programme on oral health knowledge and behaviour outcomes in children after the intervention as compared to a control group over 24 weeks.
Methods: This was a superiority cluster randomised trial of children aged 6-12 years from Indonesia (N = 2021) and Nigeria (N = 750). All children were provided with toothpaste and a toothbrush, and the intervention groups (N = 1107 and 439, respectively) received the 21-day BDN programme. Children were followed up at Weeks 3, 8, and 24 after the programme start date and completed a questionnaire addressing the objectives at all timepoints. Improvement in oral health knowledge and behaviour was calculated based on the percentage of positive change in answers and analysed based on a conditional logistic approach for each evaluation timepoint, compared with control, with a 95% CI.
Results: After 24 weeks, Indonesian children following the BDN programme presented with a 30% and 60% additional probability, respectively, of adequate timing of toothbrushing and of being aware of the importance of adequate toothbrushing frequency compared with control. In Nigeria, after 24 weeks, children following the BDN programme had a 92% and 73% higher probability of adequate toothbrushing frequency and of using fluoride toothpaste, respectively, compared with control.
Conclusions: The BDN programme is effective at improving children's knowledge and behaviour compared with a control population.
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http://dx.doi.org/10.1016/j.identj.2021.01.014 | DOI Listing |
Sci Total Environ
December 2024
FLARE wildfire research, The University of Melbourne, School of Agriculture, Food and Ecosystem Sciences, Melbourne, Victoria, Australia.
Climate change and fire management actions are the two key drivers of fire regime changes now and into the future. The predicted effects of these drivers vary between regions and global climate projections; however, it is expected that fire regimes globally are likely to intensify. Increased wildfire extent, frequency and severity mean impacts to people, property, infrastructure, production and the environment are also likely to increase under worsening climate conditions.
View Article and Find Full Text PDFJ Parkinsons Dis
October 2024
Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Background: Stigma is a relevant aspect of Parkinson's disease (PD). Specific stigma tools are needed to address the complex construct of stigma in PD comprehensively.
Objective: To test the dimensionality and psychometric properties of the newly developed Parkinson's Disease Stigma Questionnaire (PDStigmaQuest).
AJNR Am J Neuroradiol
August 2024
From the Department of Neurology, Neuroinnovation Program, Multiple Sclerosis and Neuroimmunology Imaging Program, The University of Texas Southwestern Medical Center, Peter O'Donnell Jr. Brain Institute (DTO, TMM, MM, MAP, KWB), Dallas Texas, USA; The University of Texas Southwestern Medical Center, School of Medicine (KS), Dallas, Texas, USA; Division of Neurology, University of Saskatchewan (KZ), Saskatoon, SK, Canada; Division of Neurosurgery, University of Saskatchewan (BDN), Saskatoon, SK, Canada; Texas Tech University Health Sciences Center, School of Medicine (ADS), Lubbock, Texas, USA; Université Nice Cote d'Azur (CLF), CRCSEP, Nice, France.
Background And Purpose: The study of T2-weighted hyperintense lesions resulting from autoimmune inflammatory injury and associated volumes within the CNS remains fundamental to the diagnosis and disease surveillance of multiple sclerosis (MS). We investigated the dynamic changes of individual T2-weighted hyperintense MS lesions on MRI and hypothesized that variations may be present below the threshold of visual perception when evaluating longitudinal data.
Materials And Methods: A retrospective study was performed of people with MS, incorporating data from three consecutive MRI time points acquired within a single academic center.
Nat Commun
March 2024
NanoPhotonics Centre, Cavendish Laboratory, Department of Physics, JJ Thompson Avenue, University of Cambridge, Cambridge, CB3 0HE, UK.
Surface-enhanced Raman spectroscopy (SERS) harnesses the confinement of light into metallic nanoscale hotspots to achieve highly sensitive label-free molecular detection that can be applied for a broad range of sensing applications. However, challenges related to irreversible analyte binding, substrate reproducibility, fouling, and degradation hinder its widespread adoption. Here we show how in-situ electrochemical regeneration can rapidly and precisely reform the nanogap hotspots to enable the continuous reuse of gold nanoparticle monolayers for SERS.
View Article and Find Full Text PDFBMC Neurol
October 2023
Amsterdam UMC, University of Amsterdam, Neurology, Meibergdreef 9, Amsterdam, Netherlands.
Background: The effectiveness of Deep Brain Stimulation (DBS) therapy for Parkinson's disease can be limited by side-effects caused by electrical current spillover into structures adjacent to the target area. The objective of the STEEred versus RING-mode DBS for Parkinson's disease (STEERING) study is to investigate if directional DBS for Parkinson's disease results in a better clinical outcome when compared to ring-mode DBS.
Methods: The STEERING study is a prospective multi-centre double-blind randomised crossover trial.
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