Using abstract concepts is a hallmark of human cognition. While multiple kinds of abstract concepts exist, they so far have been conceived as a unitary kind in opposition to concrete ones. Here, we focus on Institutional concepts, like justice or norm, investigating their fine-grained differences with respect to other kinds of abstract and concrete concepts, and exploring whether their representation varies according to individual proficiency. Specifically, we asked experts and non-experts in the legal field to evaluate four kinds of concepts (i.e., institutional, theoretical, food, artefact) on 16 dimensions: abstractness-concreteness; imageability; contextual availability; familiarity; age of acquisition; modality of acquisition; social valence; social metacognition; arousal; valence; interoception; metacognition; perceptual modality strength; body-object interaction; mouth and hand involvement. Results showed that Institutional concepts rely more than other categories on linguistic/social and inner experiences and are primarily characterized by positive valence. In addition, a more subtle characterization of the institutional domain emerged: Pure-institutional concepts (e.g., parliament) were perceived as more similar to technical tools, while Meta-institutional concepts (e.g., validity) were characterized mainly by abstract components. Importantly, for what concerns individual proficiency, we found that the level of expertise affects conceptual representation. Only law-experts associated Institutional concepts with exteroceptive and emotional experiences, showing also a more grounded and situated representation of the two types of institutional concepts. Overall, our finding highlights the richness and flexibility of abstract concepts and suggests that they differ in the degree of embodiment and grounding. Implications of the results for current theories of conceptual representation and social institutions are discussed.
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http://dx.doi.org/10.1007/s00426-021-01492-8 | DOI Listing |
iScience
January 2025
International Institute for Applied Systems Analysis, Laxenburg, Lower Austria, Austria.
Cost reductions are essential for accelerating clean technology deployment. Because multiple factors influence costs, traditional one-factor learning models, solely relying on cumulative installed capacity as an explanatory variable, may oversimplify cost dynamics. In this study, we disentangle learning and economies of scale effects at unit and project levels and introduce a knowledge gap concept to quantify rapid technological change's impact on costs.
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February 2025
Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, Marburg, Germany.
Unlabelled: Non-communicable diseases (NCDs) characterised by type 2 inflammation, including asthma, allergic rhinitis, chronic rhinosinusitis with nasal polyps, atopic dermatitis, food allergies and eosinophilic esophagitis, are increasing in prevalence worldwide. Currently, there is a major paradigm shift in the management of these diseases, towards the concept of disease modification and the treatment goal remission, regardless of severity and age. Remission as a treatment goal in chronic inflammatory NCDs was first introduced in rheumatoid arthritis, and then adopted in other non-type 2 inflammatory diseases.
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February 2025
Dept of Immunology, Erasmus Medical Center, Rotterdam, the Netherlands.
Background: A considerable proportion (21%) of patients with common variable immunodeficiency (CVID) suffers from depression. These subjects are characterized by reduced naïve T cells and a premature T cell senescence similar to that of patients with major depressive disorder (MDD). It is known that T cells are essential for limbic system development/function.
View Article and Find Full Text PDFExposome
February 2024
MRC Centre for Environment and Health, School of Public Health, Imperial College, London, UK.
The exposome was proposed following the realization that most human diseases have an environmental rather than a genetic (hereditary) origin. Non-communicable diseases are, in fact, the consequence of multiple exposures that activate a sequence of stages in a multistage process that already starts in early life. This attracted attention to both the multiplicity (in fact, potentially the totality) of exposures humans are exposed to since conception and to the life-long perspective of disease causation.
View Article and Find Full Text PDFPerspect Clin Res
August 2024
Department of Pharmacy Practice, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India.
Post-COVID-19, the emergence of newer technologies has taken center stage. One such technology is metaverse, which is an extension of existing technologies such as virtual reality (VR) and augmented reality (AR) that enables a fully immersive communication platform through the utilization of digital twins and avatars in a three-dimensional digital space. Literature review has shown that the adoption of such technologies in the field of clinical trials can help in improving the therapeutic outcomes in patients while having numerous other benefits.
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