Purpose: To determine the cut-off levels for choroidal thickness and choroidal vascularity index (CVI) to differentiate among pachychoroid spectrum diseases.

Study Design: A retrospective comparative study METHODS: A total of 143 eyes were included. Of these 29 had uncomplicated pachychoroid (UCP), 29 had pachychoroid pigment epitheliopathy (PPE), 25 had pachychoroid neovasculopathy (PNV), 30 had central serous chorioretinopathy (CSC), and 30 had polypoidal choroidal vasculopathy (PCV). The choroidal areas were measured with ImageJ software. The CVI, the proportion of the luminal area to the total choroidal area, was assessed.

Results: The cut-off points of central choroidal thickness were determined as 360 µm for the PPE and PCV group pair (p < 0.001), 422 µm for the PNV and CSC group pair (p = 0.026), 271 µm for the PNV and PCV group pair (p < 0.001), and 341 µm for the CSC and PCV group pair (p < 0.001). The cut-off points of CVI were 72.7 for the PPE and PCV group pair (p < 0.001), 74.7 for the PNV and CSC group pair (p = 0.005), 72.6 for the PNV and PCV group pair (p = 0.001), and 73.6 for the CSC and PCV group pair (p < 0.001).

Conclusion: Pachychoroid spectrum may be composed of a combination of distinct choroidal diseases with different vascular and structural characteristics.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10384-021-00829-5DOI Listing

Publication Analysis

Top Keywords

comparative study
8
choroidal vascularity
8
pachychoroid spectrum
8
choroidal thickness
8
choroidal
7
pachychoroid
5
study choroidal
4
vascularity determination
4
determination cut-off
4
cut-off values
4

Similar Publications

This prospective observational study aimed to compare abdominal hysterectomy (AH), vaginal hysterectomy (VH), and total laparoscopic hysterectomy (TLH) in terms of oxidative stress (OS) by measuring serum levels of total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI). Of the 3 groups, namely, AH, VH, and TLH, 22 patients were enrolled in each to investigate the aim of the study mentioned above. Patient demographics, clinical and surgical characteristics, and preoperative and postoperative (0th and 24th hours) serum TAS, TOS, and OSI levels were investigated.

View Article and Find Full Text PDF

This study compares and investigates the efficacy of 2 different surgical methods for early stage femoral head necrosis and analyze the factors affecting surgical outcomes and long-term femoral head survival. A retrospective analysis was conducted on the clinical data of 48 patients (52 hips) with femoral head necrosis who underwent either the Super-Path or Watson-Jones approach from January 1, 2016, to January 1, 2024. Harris scores at multiple time points before and after surgery were compared using repeated-measures analysis of variance (ANOVA), and a COX proportional hazards model was used to analyze risk factors.

View Article and Find Full Text PDF

Background: Sarcopenia is closely associated with a poor quality of life and mortality, and its prevention and treatment represent a critical area of research. Resistance training is an effective treatment for older adults with sarcopenia. However, they often face challenges when receiving traditional rehabilitation treatments at hospitals.

View Article and Find Full Text PDF

Mold defects pose a significant risk to the preservation of valuable fine art paintings, typically arising from fungal growth in humid environments. This paper presents a novel approach for detecting and categorizing mold defects in fine art paintings. The technique leverages a feature extraction method called Derivative Level Thresholding to pinpoint suspicious regions within an image.

View Article and Find Full Text PDF

To evaluate the diagnostic accuracy of artificial intelligence (AI) assisted radiologists and standard double-reading in real-world clinical settings for rib fractures (RFs) detection on CT images. This study included 243 consecutive chest trauma patients (mean age, 58.1 years; female, 166) with rib CT scans.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!