Aims: Early diagnosis of developmental dysplasia of the hip (DDH) using ultrasound (US) is safe, effective and inexpensive, but requires high-quality scans. The effect of scan quality on diagnostic accuracy is not well understood, especially as artificial intelligence (AI) begins to automate such diagnosis. In this paper, we developed a 10-point scoring system for reporting DDH US scan quality, evaluated its inter-rater agreement and examined its effect on automated assessment by an AI system-MEDO-Hip.
Methods: Scoring was based on iliac wing straightness and angulation; visibility of labrum, os ischium and femoral head; motion; and other artifacts. Four readers from novice to expert separately scored the quality of 107 scans with this 10-point scale and with holistic grading on a scale of 1-5. MEDO-Hip interpreted the same scans, providing a diagnostic category or identifying the scan as uninterpretable.
Results: Inter-rater agreement for the 10-point scale was significantly higher than holistic scoring ICC 0.68 vs 0.93, p < 0.05. Inter-rater agreement on the categorisation of individual features, by Cohen's kappa, was highest for os ischium (0.67 ± 0.06), femoral head (0.65 ± 0.07) and iliac wing (0.49 ± 0.12) indices, and lower for the presence of labrum (0.21 ± 0.19). MEDO-Hip interpreted all images of a quality > 7 and flagged 13/107 as uninterpretable. These were low-quality images (3 ± 1.2 vs. 7 ± 1.8 in others, p < 0.05), with poor visualization of the os ischium and noticeable motion. AI accuracy in cases with quality scores < = 7 was 57% vs. 89% on other cases, p < 0.01.
Conclusion: This study validates that our scoring system reliably characterises scan quality, and identifies cases likely to be misinterpreted by AI. This could lead to more accurate use of AI in DDH diagnosis by flagging low-quality scans likely to provide poor diagnosis up front.
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http://dx.doi.org/10.1007/s40477-021-00560-4 | DOI Listing |
EClinicalMedicine
October 2024
Department of Oncology, Queen's University, Kingston, Canada.
Patients with cancer expect prolonged life (overall survival, OS) or better life (quality of life, QOL) from cancer treatments. However, majority of new cancer drugs are now being approved not based on improved OS or QOL, but based on surrogate endpoints such as tumor shrinkage or delayed tumor progression. These surrogate endpoints, including their validity as a proxy for overall survival, differ based on disease settings and lines of treatment but in general, most surrogate measures have weak correlation with outcomes that matter to patients.
View Article and Find Full Text PDFFront Oncol
December 2024
Honorary Research Associate, Department of Operations and Quality Management, Durban University of Technology, Durban, South Africa.
Introduction: Lung cancer is one of the main causes of the rising death rate among the expanding population. For patients with lung cancer to have a higher chance of survival and fewer deaths, early categorization is essential. The goal of thisresearch is to enhance machine learning to increase the precision and quality of lung cancer classification.
View Article and Find Full Text PDFRadiat Prot Dosimetry
January 2025
Medical Physics, Ghent University, Proeftuinstraat 86, 9000 Ghent, Belgium.
Quality control (QC) of personal radiation protective equipment (PRPE) is essential to detect tears and holes in the attenuating layers. Routinely, this QC is performed using fluoroscopy on a conventional X-ray table. However, such a QC procedure is laborious and time consuming.
View Article and Find Full Text PDFJ Comput Assist Tomogr
November 2024
From the Carl E. Ravin Advanced Imaging Labs, Center for Virtual Imaging Trials, Department of Radiology.
Objective: Patient characteristics, iodine injection, and scanning parameters can impact the quality and consistency of contrast enhancement of hepatic parenchyma in CT imaging. Improving the consistency and adequacy of contrast enhancement can enhance diagnostic accuracy and reduce clinical practice variability, with added positive implications for safety and cost-effectiveness in the use of contrast medium. We developed a clinical tool that uses patient attributes (height, weight, sex, age) to predict hepatic enhancement and suggest alternative injection/scanning parameters to optimize the procedure.
View Article and Find Full Text PDFCureus
December 2024
Radiology, Azadi Teaching Hospital, Duhok, IRQ.
Background CT is among the most widely used diagnostic imaging techniques worldwide, providing significant advantages and invaluable diagnostic insights for detecting a wide range of diseases across various organs. However, it involves exposing patients to relatively high levels of ionizing radiation. Objective This study aims to document the radiation doses from chest CT scans performed at Azadi Teaching Hospital in Duhok Province and compare them with those recorded at the 3-Tesla Center for Advanced MRI and CT Scanning, also located in Duhok, using diagnostic reference levels (DRLs) as a benchmark.
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