Purpose: Crimean-Congo Hemorrhagic fever (CCHF) is a viral hemorrhagic fever which is transmitted by tick bites, or through contact with infected animal tissues or secretions during and immediately post slaughter. It can be responsible for severe outbreaks in humans.
Methods: We have explained 10 patients of CCHF, which was acquired during the first outbreak in northwest of Iran. All 10 patients were admitted to our hospital and all were treated promptly by ribavirin.
Results: In this outbreak, 51 blood samples were collected from suspected patients and sent to Pasteur Institute of Iran for additional assessments. CCHF was confirmed by reverse transcriptase polymerase chain reaction (RT-PCR) in 19.60% of patients.
Conclusion: High movement of livestock and vectors in spring and summer seasons is one of the major causes of virus circulation in northwestern Iran.
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http://dx.doi.org/10.1007/s11686-021-00342-2 | DOI Listing |
FASEB J
January 2025
State Key Laboratory of Virology, Institute of Medical Virology, Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan, Hubei, China.
Hantaan virus (HTNV) infection causes severe hemorrhagic fever with renal syndrome (HFRS) in humans and the infectious process can be regulated by autophagy. The phosphatase and tensin homolog (PTEN) protein has antiviral effects and plays a critical role in the autophagy pathway. However, the relationship between PTEN and HTNV infection is not clear and whether PTEN-regulated autophagy involves in HTNV replication is unknown.
View Article and Find Full Text PDFParasit Vectors
January 2025
Department of Agriculture, Food and Environment, University of Pisa, Pisa, Italy.
Rapid urbanization and migration in Latin America have intensified exposure to insect-borne diseases. Malaria, Chagas disease, yellow fever, and leishmaniasis have historically afflicted the region, while dengue, chikungunya, and Zika have been described and expanded more recently. The increased presence of synanthropic vector species and spread into previously unaffected areas due to urbanization and climate warming have intensified pathogen transmission risks.
View Article and Find Full Text PDFBMC Infect Dis
January 2025
EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, nº 135, Porto, 4050 - 600, Portugal.
Background: The incidence of mosquito-borne infections has increased worldwide. Mainland Portugal's characteristics might favour the (re)emergence of mosquito-borne diseases. This study aimed to characterize the spatial distribution of vectors and notification rates of imported cases of mosquito-borne infections in mainland Portugal and demarcate the areas where these geographies overlap.
View Article and Find Full Text PDFSci Rep
January 2025
Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
The ongoing emergence of SARS-CoV-2 variants, combined with antigen exposures from different waves and vaccinations, poses challenges in updating COVID-19 vaccine antigens. We collected 206 sera from individuals with vaccination-only, hybrid immunity, and single or repeated omicron post-vaccination infections (PVIs), including non-JN.1 and JN.
View Article and Find Full Text PDFCan Commun Dis Rep
January 2025
Centre for Communicable Disease and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Background: Ugandan health authorities declared an outbreak of Ebola disease (EBOD), caused by the Sudan virus, in September 2022. A rapid review was conducted to update the Public Health Agency of Canada's guidelines for infection prevention and control measures for EBOD in healthcare settings to prepare for potential introduction of cases.
Objective: Summarize the available evidence on personal protective equipment (PPE) use by healthcare workers (HCWs) to prevent exposure to and transmission of viral hemorrhagic fevers (VHFs), including Ebola virus.
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