Comparative Evaluation of Four Extraction Methods of Antioxidant Compounds from in Aqueous Medium Applying Response Surface Design.

Molecules

Área Académica de Gastronomía, Instituto de Ciencias Económico Administrativas, Universidad Autónoma del Estado de Hidalgo, Circuito La Concepción Km 2.5 Col. San Juan Tilcuautla, San Agustín Tlaxiaca, Hidalgo 42160, Mexico.

Published: February 2021

The objective of this paper is to compare conventional, ultrasound, microwave, and French press methods for the extraction of antioxidant compounds from in an aqueous medium. This plant is widely used in Mexican traditional medicine for breast cancer treatment. Despite that, there are few studies on . Two response surface designs were applied to establish the best conditions of the liberation of antioxidants from , which were determined by DPPH• and Ferric Reducing Antioxidant Power (FRAP) techniques. The total phenolic content was evaluated by the Folin-Ciocalteu method. The results showed that is a source of antioxidants (669-2128 mg ET/100 g and 553-1920 mg EFe/100 g, respectively) and phenolic compounds (2232-9929 mg EGA/100 g). Among the physical factors that were analyzed, the temperature was the determinant factor to liberate the compounds of interest by using low concentrations of the sample and short times of extraction. The French press was the most efficient method, obtaining values of antioxidant activity and phenolic compounds even higher than those reported by using extraction methods with solvents such as methanol.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922995PMC
http://dx.doi.org/10.3390/molecules26041042DOI Listing

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