Chemical investigation of the octocoral , collected in the Ie Island, Okinawa, Japan, resulted in the isolation of a new briarane-type diterpenoid, briastecholide A (), as well as the previously reported metabolites, solenolide C () and briarenolide S (). The structures of briaranes - were characterized through spectroscopic analysis, and the absolute configuration of was corroborated by a single-crystal X-ray diffraction analysis. Briarane exhibited bioactivity against the protein expression of inducible nitric oxide synthase (iNOS).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998228 | PMC |
| http://dx.doi.org/10.3390/md19030136 | DOI Listing |
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8-Hydroxybriaranes from Octocoral (Briareidae) (Kükenthal, 1908).
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February 2021
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.
Chemical investigation of the octocoral , collected in the Ie Island, Okinawa, Japan, resulted in the isolation of a new briarane-type diterpenoid, briastecholide A (), as well as the previously reported metabolites, solenolide C () and briarenolide S (). The structures of briaranes - were characterized through spectroscopic analysis, and the absolute configuration of was corroborated by a single-crystal X-ray diffraction analysis. Briarane exhibited bioactivity against the protein expression of inducible nitric oxide synthase (iNOS).
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