The propagation of ultrasonic guided waves in cortical bone has potential to inform medical caregivers about the condition of the bone structure. However, as waveguides, human long bones such as the tibia are complex in terms of their material behavior and their geometric features. They exhibit anisotropic elasticity and internal damping. For the first time, wave propagation is modelled in the irregular hollow tibial cross-section, which varies along its long axis. Semi-analytical, frequency domain, and time domain finite element analyses providing complimentary information about long-range wave propagation characteristics in such a waveguide are applied to the mid-diaphyseal region of a human tibia. Simulating the guided waves generated by a contact transducer, the signals received in axial transmission indicate the consistent presence of low phase velocity non-dispersive propagating modes. The guided waves capable of traveling long distances have strong potential for diagnosis of fracture healing.
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http://dx.doi.org/10.1016/j.ultras.2021.106407 | DOI Listing |
Neurology
January 2025
Department of Neurology, Massachusetts General Hospital, Boston.
Background And Objectives: Rolandic epilepsy (RE), the most common childhood focal epilepsy syndrome, is characterized by a transient period of sleep-activated epileptiform activity in the centrotemporal regions and variable cognitive deficits. Sleep spindles are prominent thalamocortical brain oscillations during sleep that have been mechanistically linked to sleep-dependent memory consolidation in animal models and healthy controls. Sleep spindles are decreased in RE and related sleep-activated epileptic encephalopathies.
View Article and Find Full Text PDFJ Cell Mol Med
January 2025
Ataturk Vocational School of Health Services, Department of Medical Laboratory Techniques, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.
The development and progression of osteoarthritis (OA) are believed to involve inflammation. This study aimed to investigate the effects of applying therapeutic ultrasound (US) to human osteoarthritic chondrocytes in continuous and pulsed modes on cell proliferation and proinflammatory cytokine levels. Human osteoarthritic chondrocytes (HC-OA 402OA-05a) were proliferated in appropriate media and then seeded into culture plates.
View Article and Find Full Text PDFClin Trials
January 2025
Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Background: Implementation and hybrid effectiveness-implementation trials aspire to speed the translation of science into practice by generating crucial evidence for improving the uptake of effective health interventions. By design, they pose unique recruitment and retention challenges due to their aims, units of analysis, and sampling plans, which typically require many clinical sites (i.e.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Institute of Fundamental Technological Research, Polish Academy of Sciences, ul. Pawińskiego 5B, 02-106 Warsaw, Poland.
In this paper, we demonstrate that torsional surface elastic waves can propagate along the curved surface of a metamaterial elastic rod (cylinder) embedded in a conventional elastic medium. The crucial parameter of the metamaterial rod is its elastic compliance s44(1)ω, which varies as a function of frequency ω analogously to the dielectric function εω in Drude's model of metals. As a consequence, the elastic compliance s44(1)ω can take negative values s44(1)ω<0 as a function of frequency ω.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
Interlevel Clinical Management Unit of Physical Medicine and Rehabilitation, Reina Sofía University Hospital, Córdoba and Guadalquivir Health District, 14011 Córdoba, Spain.
: Shoulder pain is a very common health issue among adults, being 8% due to calcifying tendinopathies (CT) of the shoulder. The evolutionary process of this lesion can be classified according to Bianchi Martinoli, depending on the ultrasound appearance. In 50% of cases, with first-line treatments, they resolve spontaneously.
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