Background: Strongyloides stercolaris is one of the most important intestinal nematodes due to its worldwide distribution. It’s estimated that it affects 50 to 100 million people in 70 countries of the world. In a large percentage of cases it is asymptomatic, however, patients with immunosuppression may present more serious symptoms. The life cycle of this parasite comprises two phases: one as a free-living organism and the other as a parasite. The objective of this case report is to describe the histological findings compatible with this parasitosis and the importance of recognizing them in order to provide adequate and timely treatment.
Case Report: This is a 37-year-old male patient who began his condition in December 2018, with an acute respiratory condition that occurs after a diarrheal event. Due to the initial evolution, the presumptive diagnosis of Crohn’s disease was made, treated with prednisone without showing improvement. During follow-up, stomach and duodenal biopsies were performed, among others, which allowed the detection of S. stercolaris, which was managed with ivermectin.
Conclusions: The case presented agrees with what is referred to in the consulted literature, as it demonstrates the wide spectrum of clinical manifestations, the relationship with immunosuppression states and how frequent it is to make a first-instance erroneous diagnosis. Likewise, it exemplifies the difficulty involved in making the diagnosis of a parasitosis through histological study, due to the particularities of the parasite itself, as well as the little familiarity that the surgical pathologist may have due to how unusual this pathology is outside of tropical environments.
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http://dx.doi.org/10.24875/RMIMSS.M21000056 | DOI Listing |
Clin Cosmet Investig Dermatol
January 2025
Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Lymphomatoid papulosis (LyP) is currently categorized as a primary lymphoproliferative disorder that follows a chronic, recurrent clinical course. The diagnosis of LyP is mainly based on clinical presentation and histopathological correlation. Six subtypes of LyP have been described and recognized, each with different histological features and sometimes distinct clinical presentations.
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July 2025
Head of School, Sepsis, and Limb Reconstruction, Nelson Mandela School of Clinical Medicine, College of Health Sciences, University of KwaZulu-Natal, 719 Umbilo Road, 4001, Durban, South Africa.
Background: Disease progression (DP) of osteosarcomas, albeit with aggressive treatments, hinders improving survival. The DP patterns are unique in low- and middle-income countries like South Africa. We determine the prognostic factors associated with disease progression (DP) of the appendicular skeleton's central high-grade conventional osteosarcoma (COS).
View Article and Find Full Text PDFCureus
January 2025
Internal Medicine, Hospital Senhora da Oliveira, Guimarães, PRT.
Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Despite primarily affecting the lung, sarcoidosis can affect any organ, resulting in various clinical manifestations. We present a case of a 56-year-old man who developed thoracic pain over several months along with skin lesions.
View Article and Find Full Text PDFCureus
December 2024
Dermatology and Venereology, Faculty of Medicine, Al-Azhar University, Cairo, EGY.
Wells' syndrome is a rare inflammatory disease characterized by recurrent, erythematous plaques with histological flame figures, which can be associated with idiopathic hypereosinophilic syndrome (IHES). We present a case of a nine-year-old boy who presented with a one-year history of an itchy rash on his legs associated with peripheral eosinophilia. The rash initially started as an annular plaque and developed raised borders with central hyperpigmentation.
View Article and Find Full Text PDFCureus
December 2024
Obstetrics and Gynecology, Marunouchi Hospital, Matsumoto, JPN.
Malignant transformation is a rare complication of ovarian mature cystic teratoma that occurs in 1-3% of cases. We herein report a case of squamous cell carcinoma originating from mature cystic teratoma of the ovary diagnosed 10 years after initial tumor detection. A 69-year-old woman presented to the Department of Internal Medicine with a seven-month history of abdominal fullness.
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