Background: Breast cancer is the main cause of death by cancer in Mexican women. High mammographic breast density is a well-established breast cancer risk factor that also increases the risk of death. However, there is limited data of breast density patterns among Mexican women and their association with breast cancer incidence and mortality.
Objective: To determine the distribution of breast density patterns and BI-RADS (Breast Imaging Reporting and Data System) among women from Torreon, Coahuila.
Method: Observational and retrospective study. Mammographic reports of women from Torreon, Mexico, were analyzed. Reports came from IMSS HGZ#16, Sanatorio Español and a private radiological office. Only mammographic records which described age, breast density and Bi-RADS reports were included. Differences on breast density distribution were analyzed with the Chi-Square test according to age, economic sectors and BI-RADS classification.
Results: A total of 2,187 women were included, representing about 1% of the total adult women population of Torreon. The mean age was 54.4 years, and the mammographic density patterns distribution was: 19.15% fatty, 47.76% fibroglandular density, 27.10% heterogeneously dense, and 5.99% extremely dense.
Conclusions: The main pattern in this Mexican population is the fibroglandular density, and extremely dense breast was only 6%. Our results suggest that non-dense breast tissue could increase breast cancer risk. Further studies on related risk factors, like body mass index are required.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.24875/RMIMSS.M21000053 | DOI Listing |
J Transl Med
January 2025
Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Background: HER2-targeted therapies have revolutionized the treatment of HER2-positive breast cancer patients, leading to significant improvements in tumor response rates and survival. However, resistance and incomplete response remain considerable challenges. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition is a novel therapeutic strategy for the management of dyslipidemia by enhancing the clearance of low-density lipoprotein cholesterol receptors, however recent evidence also shows links between PCSK9 and cancer cells.
View Article and Find Full Text PDFJ Craniofac Surg
January 2025
Department of Plastic Surgery, The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People's Hospital).
Introduction: The strategy of adipose component transplantation has been proposed and widely used in both reconstructive and aesthetic surgery. However, there is no uniform standard for the preparation of component fat, and the volume calculation of liposuction and injection in clinical applications is mostly based on experience. This study aims to analyze the volume of component fat obtained during clinical series.
View Article and Find Full Text PDFData Brief
February 2025
Department of Geoinformatics, University of Kashmir, Hazratbal Srinagar 190006, Jammu and Kashmir, India.
Accurate estimates of forest dynamics and above-ground forest biomass for the topographically challenging Himalaya are crucial for understanding carbon storage potential, assessing ecosystem services, and guiding conservation efforts in response to climate change. This dataset provides a manually delineated multi-temporal forest inventory and a comprehensive record of above-ground biomass (AGB) across the Kashmir Himalaya, generated from field observations, advanced remote sensing and machine learning. Data were collected and generated through remote sensing techniques and extensive in-situ measurements of 6220 trees (n=275 plots), including tree diameter at breast height, species composition, and tree density to map forest area and model AGB across varied terrain.
View Article and Find Full Text PDFInt J Breast Cancer
January 2025
Department of Hematology and Oncology, Houston Methodist Dr Mary and Ron Neal Cancer Center, Houston, Texas, USA.
This study evaluates the effects of hydroxytyrosol (HT), a component of olive oil, on mammographic breast density reduction. We explored effects of HT on Wnt -catenin and other pathways involved in cancer stem cell renewal, DNA repair, cell proliferation, and differentiation. Twenty-five milligrams per day oral dose of HT was given for 12 months in pre- and postmenopausal women at increased risk of breast cancer.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Department of Diagnostic Imaging, Oncological Radiotherapy, and Hematology, Diagnostic Imaging Area, Italy.
Pregnancy-associated breast cancer (PABC) presents unique challenges. This type of breast cancer is often more aggressive than that diagnosed in nonpregnant women, and its diagnosis is frequently delayed. Several factors contribute to this delay, including the physiological changes that occur during pregnancy, such as breast enlargement, breast tenderness and increased tissue density, which can mask early signs of malignancy.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!