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| http://dx.doi.org/10.4103/ijp.IJP_635_19 | DOI Listing |
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From the first pilot initiatives in the early 1990s to the national OSIAP survey in the 2020s: More than 30years of insight in medication diversion phenomenon in France.
Therapie
October 2024
Centre d'Évaluation et d'Information sur la Pharmacodépendance - Addictovigilance, Service de Pharmacologie Médicale et Clinique, Hôpitaux de Toulouse, Université de Toulouse, 31000 Toulouse, France.
This article proposes to trace back the timeline of the monitoring of falsified medical prescriptions in France as part of the French Addictovigilance System's toolbox. It examines the genesis of the OSIAP survey (Suspect Prescriptions Indicator of Possible Abuse), which has been held at the national level since 2001 but was created in the early 1990s, and its development until the current situation with a continuously confirmed yearly increasing trend. Understanding the birth and development of OSIAP and some other Addictovigilance tools that continue to be useful after more than 30 years of existence requires to review key historical benchmarks including the principles and missions of the former French National Commission on Narcotic and Psychotropic Drugs.
View Article and Find Full Text PDFTropicamide-induced psychosis in the context of chemsex practices treated in an emergency department.
Emergencias
June 2024
Departamento de Psiquiatría y Psicología Clínica, Hospital Clínic de Barcelona, España. Unidad de Conductas Adictivas, Instituto Clínico de Neurociencias, Hospital Clínic de Barcelona, España. Health and Addictions Research Grup, IDIBAPS, Universitat de Barcelona, Red de Investigación en Atención Primaria de Adicciones, RIAPAd (RICORS), Barcelona, España.
Pupillary response to percutaneous auricular vagus nerve stimulation in alcohol withdrawal syndrome: A pilot trial.
Alcohol
February 2024
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Austria; Comprehensive Center for Clinical Neurosciences and Mental Health (C3NMH), Medical University of Vienna, Austria.
Background: Autonomic symptoms in alcohol withdrawal syndrome (AWS) are associated with a sympathetic-driven imbalance of the autonomic nervous system. To restore autonomic balance in AWS, novel neuromodulatory approaches could be beneficial. We conducted a pilot trial with percutaneous auricular vagus nerve stimulation (pVNS) in AWS and hypothesized that pVNS will enhance the parasympathetic tone represented by a reduction of pupillary dilation in a parasympatholytic pharmacological challenge.
View Article and Find Full Text PDF[Determining the time of intoxication due to non-drug use of tropicamide].
Sud Med Ekspert
October 2022
Municipal Substance Abuse Hospital No. 1, St. Petersburg, Russia.
The study objective is to develop approaches to the retrospective assay of tropicamide in biological fluids and hair. The study was performed using the substance of tropicamide. Sample preparation included hydrolysis with the following enzymes: papain, chymotrypsin, trypsin, chymopsin, and hyaluronidase.
View Article and Find Full Text PDFAbuse of tropicamide eye drops: review of clinical data.
Braz J Psychiatry
November 2022
Department of Psychiatry, University of Missouri, Kansas City, MO, USA.
Over the past 15 years, the increasing nonmedical use of tropicamide ophthalmic drops has been reported in Europe, coinciding with an increase in opioid addiction and drug-related mortality. Although tropicamide is generally known as a cheap alternative to heroin in Eastern Europe, it still appears to be a relatively new phenomenon that has arisen over the last decade. A narrative review was conducted of all the relevant sources published in more than five countries between January 1, 1975 and January 10, 2021.
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