Introduction: Despite the development of non-fluoroscopic catheter visualization options, fluoroscopy is still used in most ablation procedures. The aim of this multicenter study was to evaluate the safety and efficacy of a new ultra-low dose radiation protocol for EP procedures in a large number of patients.
Methods And Results: A total of 3462 consecutive patients (male 1926 (55.6%), age 64.4 ± 14.0 years, BMI 26.65 ± 4.70) undergoing radiofrequency ablation (left atrial (n = 2316 [66.9%], right atrial (n = 675 [19.5%], or ventricular (n = 471 [13.6%]) in three German centers were included in the analysis. Procedures were performed using a new ultra-low dose protocol operating at 8nGy for fluoroscopy and 36nGy for cine-loops. Additionally a very low framerate (2-3FPS) was used. Using the new protocol very low Air kerma-area product (KAP) values were achieved for left atrial ablations (104.25 ± 84.22 μGym ), right atrial ablations (70.98 ± 94.79 μGym ) and ablations for ventricular tachycardias or PVCs (78.62 ± 66.59 μGym ). Acute procedural success was achieved in 3289/3388 (97.1%) while the rate of major complications was very low compared to previously published studies not using low dose settings (n = 20, 0.6%).
Conclusion: The ultra-low dose, low framerate protocol leads to very low radiation doses for all EP procedures while neither procedural time, fluoroscopy time nor success or complication rates were compromised. When compared to current real-world Air KAP data the new ultra-low dose fluoroscopy protocol reduces radiation exposure by more than 90%.
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http://dx.doi.org/10.1111/pace.14205 | DOI Listing |
Mar Drugs
November 2024
Key Laboratory of Cultivation and High-Value Utilization of Marine Organisms in Fujian Province, Fisheries Research Institute of Fujian, National Research and Development Center for Marine Fish Processing, Xiamen 361021, China.
Tetrodotoxin (TTX) is a neurotoxin that binds to sodium channels and blocks sodium conduction. Importantly, TTX has been increasingly detected in edible aquatic organisms. Because of this and the lack of specific antidotes, TTX poisoning is now a major threat to public health.
View Article and Find Full Text PDFEur Radiol
December 2024
Thoracic Surgery Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Objectives: To assess the consistency of automated measurements of coronary artery calcification (CAC) burden and emphysema extent on computed tomography (CT) images acquired with different radiation dose protocols in a lung cancer screening (LCS) population.
Materials And Methods: The patient cohort comprised 361 consecutive screenees who underwent a low-dose CT (LDCT) scan and an ultra-low-dose CT (ULDCT) scan at an incident screening round. Exclusion criteria for CAC measurements were software failure and previous history of CVD, including coronary stenting, whereas for emphysema assessment, software failure only.
Med Phys
December 2024
Siemens Healthineers AG, Forchheim, Germany.
Background: Photon counting computed tomography (PCCT) employs direct and spectrally resolved counting of individual x-ray quanta, enhancing image quality compared to the standard energy-integrating CT (EICT).
Purpose: To evaluate the quantitative improvements in CT image quality metrics by comparing the first medical PCCT with a state-of-the-art EICT.
Methods: The PCCT versus EICT noise improvement ratio R was derived from the quantum statistics of the measurement process and measured across the clinical x-ray flux range for both systems.
Transplant Cell Ther
November 2024
The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:
BJR Open
January 2024
Radiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Objective: There is a lack of recent meta-analyses and systematic reviews on the use of ultra-low-dose CT (ULDCT) for the detection, measurement, and diagnosis of lung nodules. This review aims to summarize the latest advances of ULDCT in these areas.
Methods: A systematic review of studies in PubMed and Web of Science was conducted, using search terms specific to ULDCT and lung nodules.
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