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Nutrition Users' Guides: RCTs Part 2 - structured guide for interpreting and applying study results from randomised controlled trials on therapy or prevention questions.
BMJ Nutr Prev Health
August 2024
Department of Nutrition, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas, USA.
This article continues from a prior commentary on evaluating the risk of bias in randomised controlled trials addressing nutritional interventions. Having provided a synopsis of the risk of bias issues, we now address how to understand trial results, including the interpretation of best estimates of effect and the corresponding precision (eg, 95% CIs), as well as the applicability of the evidence to patients based on their unique circumstances (eg, patients' values and preferences when trading off potential desirable and undesirable health outcomes and indicators (eg, cholesterol), and the potential burden and cost of an intervention). Authors can express the estimates of effect for health outcomes and indicators in relative terms (relative risks, relative risk reductions, OR or HRs)-measures that are generally consistent across populations-and absolute terms (risk differences)-measures that are more intuitive to clinicians and patients.
View Article and Find Full Text PDFImpact of Heat on Human and Animal Health in India: A Landscape Review.
Dialogues Health
June 2025
Department of Public Health Science, Indian Institute of Public Health Gandhinagar (IIPHG), Gujarat, India.
Climate change presents a significant global public health challenge for animals and humans. Due to geography, climate, population, and urbanization, India is vulnerable to extreme heat. This review aims to explore the impact of heat on human and animal health in India.
View Article and Find Full Text PDFThe selective sorting of miR-4432 into endothelial extracellular vesicles is controlled by a specific RNA binding protein: New Insights in the pathophysiology of venous malformations.
Br J Dermatol
January 2025
Department of Medicine (Division of Cardiology), Wilf Family Cardiovascular Research Institute, Einstein Institute for Neuroimmunology and Inflammation (INI), Einstein Institute for Aging Research, Albert Einstein College of Medicine, New York City, NY.
Nonnegligible cascading impacts of global urban expansion on net primary productivity.
PNAS Nexus
January 2025
Key Laboratory of Geographic Information Science (Ministry of Education), School of Geographic Sciences, East China Normal University, Shanghai 200241, China.
Accelerated global urban expansion not only directly occupies surrounding ecosystems, but also induces cascading losses of natural vegetation elsewhere through cropland displacement. Yet, how such effects alter the net primary productivity (NPP) worldwide remains unclear. Here, we quantified the direct and cascading impacts of global urban expansion on terrestrial NPP from 1992 to 2020 and projected the impacts under the shared socioeconomic pathways framework by 2100.
View Article and Find Full Text PDFGenerative artificial intelligence in graduate medical education.
Front Med (Lausanne)
January 2025
Clinical Informatics Fellowship Program, Baylor Scott & White Health, Round Rock, TX, United States.
Generative artificial intelligence (GenAI) is rapidly transforming various sectors, including healthcare and education. This paper explores the potential opportunities and risks of GenAI in graduate medical education (GME). We review the existing literature and provide commentary on how GenAI could impact GME, including five key areas of opportunity: electronic health record (EHR) workload reduction, clinical simulation, individualized education, research and analytics support, and clinical decision support.
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