The novel HLA-DPB1*04:01:51 allele first described in a potential bone marrow donor from Brazil.
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Identification of the Novel HLA-DPB1*01:01:15 Allele by Next-Generation Sequencing.
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December 2024
HLA laboratory, Department of Pathology, Westchester Medical Center, Valhalla, New York, USA.
We describe the novel HLA-DPB1*01:01:15 allele found in a female African American.
View Article and Find Full Text PDFIdentification of the Novel HLA-DPB1*03:01:27 Allele by Next-Generation Sequencing.
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December 2024
Strand Life Sciences, Bangalore, Karnataka, India.
The novel HLA-DPB1*03:01:27 allele differs from HLA-DPB1*03:01:01 by one nucleotide substitution in codon 199 exon 4.
View Article and Find Full Text PDFCharacterisation of the Novel HLA-DPB1*1641:01 Allele by Next-Generation Sequencing.
HLA
December 2024
Department of Medical Genetics, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming, Yunnan, China.
Article Synopsis
- - HLA-DPB1*1641:01 and DPB1*02:02:01:01 are two variants of the HLA-DPB1 gene.
- - They differ by a single nucleotide change, where a guanine (G) at position 668 is substituted with an adenine (A).
- - This nucleotide substitution occurs specifically in exon 4 of the gene, which can affect the function or expression of the protein it encodes.
Identification of a novel immune-related gene signature by single-cell and bulk sequencing for the prediction of the immune landscape and prognosis of breast cancer.
Cancer Cell Int
December 2024
Department of Thyroid and Breast Surgery, The Second Affiliated Hospital of Soochow University, Jiangsu, China.
Background: As a common cause of cancer-related deaths in women, BRCA (breast cancer) shows complexity and requires precise biomarkers and treatment methods. This study delves into the molecular makeup of BRCA, focusing on immune profiles, molecular subtypes, gene expression and single-cell analysis.
Methods: XCell was used to assess immune infiltration based on TCGA (the Cancer Genome Atlas) data and the clustering analysis was made.
The Novel HLA-DPB1*1327:01 Allele Identified by Next-Generation Sequencing in a Potential Haematopoietic Stem Cell Donor.
HLA
December 2024
Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, Saskatchewan, Canada.
The novel allele HLA-DPB1*1327:01 has a non-synonymous mutation difference compared with HLA-DPB1*04:01:01.
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