Objective: It is uncertain why a b-value range of 1500-2000 s/mm² is optimal. This study was aimed at qualitatively and quantitatively analyzing the optimal b-value range of synthetic diffusion-weighted imaging (sDWI) for evaluating prostatic index lesions.

Materials And Methods: This retrospective study included 92 patients who underwent DWI and targeted biopsy for magnetic resonance imaging (MRI)-suggested index lesions. We generated sDWI at a b-value range of 1000-3000 s/mm² using dedicated software and true DWI data at b-values of 0, 100, and 1000 s/mm². We hypothesized that lesion conspicuity would be best when the background (i.e., MRI-suggested benign prostatic [bP] and periprostatic [pP] regions) signal intensity (SI) is suppressed and becomes homogeneous. To prove this hypothesis, we performed both qualitative and quantitative analyses. For qualitative analysis, two independent readers analyzed the b-value showing the best visual conspicuity of an MRI-suggested index lesion. For quantitative analysis, the readers assessed the b-value showing the same bP and pP region SI. The 95% confidence interval (CI) or interquartile range of qualitatively and quantitatively selected optimal b-values was assessed, and the mean difference between qualitatively and quantitatively selected b-values was investigated.

Results: The 95% CIs of optimal b-values from qualitative and quantitative analyses were 1761-1805 s/mm² and 1640-1771 s/mm² (median, 1790 s/mm² vs. 1705 s/mm²; = 0.003) for reader 1, and 1835-1895 s/mm² and 1705-1841 s/mm² (median, 1872 s/mm² vs. 1763 s/mm²; = 0.022) for reader 2, respectively. Interquartile ranges of qualitatively and quantitatively selected optimal b-values were 1735-1873 s/mm² and 1573-1867 s/mm² for reader 1, and 1775-1945 s/mm² and 1591-1955 s/mm² for reader 2, respectively. Bland-Altman plots consistently demonstrated a mean difference of less than 100 s/mm² between qualitatively and quantitatively selected optimal b-values.

Conclusion: b-value range showing a homogeneous background signal may be optimal for evaluating prostatic index lesions on sDWI. Our qualitative and quantitative data consistently recommend b-values of 1500-2000 s/mm².

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154789PMC
http://dx.doi.org/10.3348/kjr.2020.0836DOI Listing

Publication Analysis

Top Keywords

b-value range
20
qualitatively quantitatively
20
s/mm²
18
quantitatively selected
16
1500-2000 s/mm²
12
evaluating prostatic
12
qualitative quantitative
12
selected optimal
12
optimal b-values
12
range 1500-2000
8

Similar Publications

A smartphone-based fluorescent sensing system for simultaneous visual detection of chromium(Ⅲ) and copper(Ⅱ) ions.

Spectrochim Acta A Mol Biomol Spectrosc

December 2024

Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Colleges Universities Key Laboratory of Optic-electric Chemo/Biosensing and Molecular Recognition, Guangxi Minzu University, Nanning 530006, China.

In this work, we developed a highly accurate and sensitive two-emission fluorescence sensor, integrated with a smartphone, for the rapid detection of Cu and Cr in aqueous solution. This sensor comprised AgInS/ZnS quantum dots (AIS/ZnS QDs) and metal-AIEgen frameworks (MAFs). Upon mixing in a specific ratio, the hybrid system can emit a white light when exposed to a UV lamp (365 nm).

View Article and Find Full Text PDF

Hydrogel-based colorimetric power-saving sensors for on-site detection of chloride ions and glucose in sweat.

Biosens Bioelectron

December 2024

Department of Materials Science and Engineering, National Yang Ming Chiao Tung University, 1001 University Road, Hsinchu, 30010, Taiwan. Electronic address:

Noninvasive diagnostics play a crucial role in health monitoring and disease detection. Sweat is a representative sample type containing various clinical biomarkers that provide information on certain disease risks. We developed a hydrogel-based colorimetric sensor for sweat analysis using a low-power battery.

View Article and Find Full Text PDF

This research delved into the management approach for within the Gajner Beel of northwestern Bangladesh, employing a comprehensive array of length-based indicators. The study encompassed an investigation into population structure, growth parameters (including asymptotic length ( ), asymptotic weight ( ), growth coefficient (), and age at zero length ( )), mortality parameters, growth performance indices, recruitment pattern, exploitation rate (), relative yield per-recruit (), optimum catchable length , longevity, biomass, and maximum sustainable yield (. The TL and BW ranged from 5.

View Article and Find Full Text PDF

Virtual MR Elastography and Multi-b-value DWI Models for Predicting Microvascular Invasion in Solitary BCLC Stage A Hepatocellular Carcinoma.

Acad Radiol

December 2024

Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China (Z.C., Y.Z., L.W., R.C., B.F., W.C., M.L., D.L., S.W., M.H., Y.M., X.M., X.Z.). Electronic address:

Rationale And Objectives: To evaluate the performance of virtual MR elastography (vMRE) for predicting microvascular invasion (MVI) in Barcelona Clinic Liver Cancer (BCLC) stage A (≤ 5.0 cm) hepatocellular carcinoma (HCC) and to construct a combined nomogram based on vMRE, multi-b-value DWI models, and clinical-radiological (CR) features.

Methods: Consecutive patients with suspected HCC who underwent multi-b-value DWI examinations were prospectively collected.

View Article and Find Full Text PDF

Chemical and boron isotope characteristics of snow in the qiyi glacier, Qinghai-Tibet Plateau.

Environ Pollut

November 2024

Shaanxi Key Laboratory of Earth Surface System and Environmental Carrying Capacity, College of Urban and Environmental Science, Northwest University, Xi'an 710127, China; State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi'an 710061, China. Electronic address:

Snow is a valuable carrier for recording atmospheric information and snowmelt constitutes a crucial hydrological resource for ecosystem sustainability and human activities. The agriculture, industry, livelihoods and ecological security in the Hexi Corridor are dependent on the support of glacier snowmelt in Qilian Mountains of Qinghai-Tibet Plateau. We investigated the main water-soluble ions, trace elements and boron isotopes composition of snow at different altitudes in the Qiyi Glacier of the Qilian Mountains from 12 to 23, Aug.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!