•Of the fewer than 100 FATWO case reports published, at least 25 reports have metastatic quality.•Very little information regarding optimal management of FATWO is known; immunohistochemical stains may help guide therapy.•FATWO may be more of a low malignant potential entity, and patients with the diagnosis should be followed closely.
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http://dx.doi.org/10.1016/j.gore.2021.100726 | DOI Listing |
BMJ Case Rep
July 2024
Cytology & Gynaecological Pathology, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Female Adnexal Tumour of probable Wolffian Origin (FATWO) is a rare gynaecological neoplasm of low malignant potential believed to originate from mesonephric remnants. Its rarity, non-specific presentation, histological heterogeneity and ill-defined radiological features make diagnosing them challenging.A female in her 60s presented with history of lower abdominal pain for 2 years.
View Article and Find Full Text PDFJ Surg Case Rep
May 2022
Department of Surgery, General Hospital, Sarajevo 71 000, Bosnia and Herzegovina.
Female adnexal tumors of probable Wolffian origin (FATWOs) are extremely rare tumors, with only around 100 cases published worldwide. FATWOs are most frequently found in the broad ligament, but these can also appear in the mesosalpinx, Fallopian tube, ovary, paravaginal region or peritoneum. We present a case of a 68-year-old female with a history of painless abdominal distension and frequent urination, with palpable big abdominal mass.
View Article and Find Full Text PDFActa Endocrinol (Buchar)
January 2021
"Iuliu Hatieganu" University of Medicine and Pharmacy, Faculty of Medicine - Mother & Child, Emergency County Hospital, 2 Pediatric Clinic, Cluj-Napoca, Romania.
Context: Female adnexal tumors of probable Wolffian origin (FATWO) represent very rare borderline ovarian tumors with low malignant potential. Only 15 cases of malignant FATWO are described in the current literature, among which, only 5 are reported as being recurrent.
Objective: Due to the rare presentation of the recurrence of the malignant FATWO and the few cases reported in the scientific database, there are no clear therapy recommendations.
Gynecol Oncol Rep
August 2021
Instituto do Cancer do Estado de Sao Paulo - Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.
Female adnexal tumor of probable Wolffian origin (FATWO) are a rare type of cancer that originates from Wolffian duct remnants. Due to its rarity, no standard systemic treatment is established for cases of recurrent or metastatic disease. Previous literature reported the use of platinum-based chemotherapy and c-Kit tyrosine kinase inhibitors for FATWO cases with c-Kit positive expression.
View Article and Find Full Text PDFOpen Med (Wars)
June 2021
Clinical Center of Montenegro, Department of Pathology, University of Montenegro-Faculty of Medicine, Podgorica, Montenegro.
Background: During embryonic development in women, a regression of temporary embryonic structures - mesonephric (Wolffian) ducts occurs. Adnexal tumors of Wolffian duct origin (FATWO) are rare.
Case Report: We presented the case of a 64-year-old female patient who was diagnosed with FATWO.
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