AI Article Synopsis

  • - Lipid rafts are specialized areas in cell membranes that help regulate signaling pathways in eukaryotic cells.
  • - The lipid makeup of these rafts is essential for maintaining their structure and ensuring proper signaling functions.
  • - The text outlines a method for extracting lipid rafts from cultured cells, along with ways to analyze their lipid composition.

Article Abstract

Lipid rafts are distinct liquid-ordered domains of plasma membranes of most eukaryotic cells providing platform for signaling pathways. Lipid composition of rafts is critical for their structural integrity and for regulation of signaling pathways originating from rafts. Here we provide a protocol to isolate lipid rafts from cultured human and animal cells and comprehensively analyse their lipid composition.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842516PMC
http://dx.doi.org/10.21769/BioProtoc.3670DOI Listing

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