NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY.

Bio Protoc

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Rd, Oxford OX1 3TA, UK.

Published: July 2020

In drug development programmes, multiple assays are needed for the determination of protein-compound interactions and evaluation of potential use in assays with protein-protein interactions. In this protocol we describe the waterLOGSY NMR method for confirming protein-ligand binding events.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842718PMC
http://dx.doi.org/10.21769/BioProtoc.3666DOI Listing

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