Polycystic ovary syndrome (PCOS) is a prevalent reproductive-metabolic disorder with poorly understood etiology. Mimouni et al. (2021) demonstrate global genomic DNA hypomethylation in women with PCOS and their daughters, and in F3 generation PCOS-like mice, together with substantial normalization of PCOS-like mice by methyl donor dietary supplementation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133658 | PMC |
| http://dx.doi.org/10.1016/j.cmet.2021.02.008 | DOI Listing |
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