How does obesity promote breast cancer tumor growth?

Cell Metab

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD 20892, USA. Electronic address:

Published: March 2021

Obesity is a risk factor for many cancers. Maguire et al. (2021) found increased creatine synthesis by the adipocytes adjacent to breast cancers in obese mice. The creatine is transported into the cancer cells, producing larger tumors, possibly due to greater energy availability.

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Source
http://dx.doi.org/10.1016/j.cmet.2021.02.011DOI Listing

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