In this paper, we describe the clinical presentation of 2 patients with atypical Takotsubo syndrome recently observed in our hospital. It is the occasion de review the clinical characteristics, the biological markers, the imaging clues as well as the diagnosis criteria, the treatment algorithm and the prognostic of this disease, first described 30 years ago by our Japanese colleagues. The current knowledge of this recently summarized entity in an international expert consensus document is the main reference of this presentation.

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