Reversible leukoencephalopathy caused by 2 rodenticides bromadiolone and fluoroacetamide: A case report and literature review.

Rationale: With the easy access, rodenticide poisoning has been a public health problem in many countries. Characteristics of central nervous system (CNS) lesions induced by rodenticides are scarcely reported.

Patient Concerns: We presented a case of a 40-year-old man with seizure and consciousness disorder, coagulation dysfunction, and symmetric lesions in white matter and corpus callosum.

Diagnosis: He was diagnosed with rodenticide poisoning due to bromadiolone and fluoroacetamide.

Interventions: He was treated with vitamin K, hemoperfusion, acetamide, and calcium gluconate.

Outcomes: His leukoencephalopathy was reversed rapidly with the improvement of clinical symptoms.

Lessons: This report presented the impact of rodenticide poisoning on CNS and the dynamic changes of brain lesions, and highlighted the importance of timely targeted treatments.