AI Article Synopsis
- Decision-making involves selecting one option from multiple alternatives, often analyzed through tasks like the Iowa gambling task (IGT) that simulate real-life uncertainties.
- Researchers have adapted the IGT for mice, introducing a protocol that includes four options with ambiguous outcomes, immediate and long-term rewards, and a total of 100 trials without prior learning of the outcomes.
- This protocol is significant as it allows for the examination of decision-making strategies in mice, highlighting individual differences in how they approach complex decision-making scenarios.
Article Abstract
Decision-making is a complex cognitive process which consists of choosing one option among several alternatives. In humans, this process is featured in the Iowa gambling task (IGT), a decision-making task that mimics real life situations by reproducing uncertain conditions based on probabilistic rewards or penalties (see Background). Several authors wanted to adapt the IGT in rodents with subtle differences in protocols that match various aspects of the human task. Here we propose, for the first time in mice, a protocol that contains the most important characteristics of the IGT: 4 different options, choices based on 4 ambiguous outcomes with immediate and long term rewards, a total of 100 trials, no learning of the contingency before the task, and presence of both a certain reward and a probable penalty. During this task, mice have to choose between options more or less advantageous in the short and long term by developing a decision-making strategy that differs between individuals. Therefore, the strength of this protocol is that it is one of the first to enable the study of decision-making in a complex situation, and demonstrates inter-individual differences regarding decision-making strategies in mice.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842597 | PMC |
| http://dx.doi.org/10.21769/BioProtoc.3479 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identifying neural markers of clinical symptom fluctuations is prerequisite to developing more precise brain-targeted treatments in psychiatry. We have recently shown that working memory (WM) in healthy adults is dependent on the rise and fall interplay between alpha/beta and gamma bursts within frontoparietal regions, and that deviations in these patterns lead to WM performance errors. However, it is not known whether such bursting deviations underlie clinically relevant WM-related symptoms or clinical status in individuals with WM deficits.
View Article and Find Full Text PDFThe more random people's preference judgments are, the more they explore in gambling tasks.
BMC Psychol
December 2024
Graduate School of Humanities and Social Sciences, Hiroshima University, 1-1-1 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8524, Japan.
Background: The decision-making process has been investigated separately in the context of externally guided decision-making (EDM, e.g., a gambling task) and internally guided decision-making (IDM, e.
View Article and Find Full Text PDFDeep transcranial magnetic stimulation for adolescents with treatment-resistant depression: Behavioral and neural correlates of clinical improvement.
J Affect Disord
December 2024
Department of Psychology, University of Minnesota, Minneapolis, MN, USA; Center for Depression, Anxiety, and Stress Research, McLean Hospital, Belmont, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Background: Affective bias toward negativity is associated with depression and may represent a promising treatment target. Stimulating the dorsolateral prefrontal cortex (dlPFC) with deep Transcranial Magnetic Stimulation (dTMS) could lead to shifts in affective bias. The current study examined behavioral and neural correlates of affective bias in the context of dTMS in adolescents with treatment-resistant depression (TRD).
View Article and Find Full Text PDFDecision-making using the Iowa gambling test in unaffected first-degree relatives of obsessive-compulsive disorder: Comparison with healthy controls and patients with obsessive-compulsive disorder.
J Neuropsychol
December 2024
Department of Neuropsychiatry, Kyushu University Hospital, Fukuoka, Japan.
Decision-making has been suggested as an endophenotype candidate for obsessive-compulsive disorder (OCD). However, few studies have examined whether decision-making under ambiguity is an endophenotype of OCD. This study aimed to investigate decision-making under ambiguity, as assessed by the Iowa Gambling Task (IGT), in patients with OCD and unaffected first-degree relatives (UFDR).
View Article and Find Full Text PDFA demonstration of superior judgement? Exploring league of legends players' performance in risky and ambiguous decision-making tasks.
Acta Psychol (Amst)
November 2024
School of Psychology, Shanghai University of Sport, Shanghai, China. Electronic address:
In three studies, we investigated how League of Legends (LOL) game experience and game skill relate to players' performance in the Iowa Gambling Task (IGT), Balloon Analogue Risk Task (BART), and Probability Discounting Task (PDT). Additionally, the present study examined the relationship between players' in-game risk preferences and their performance in three types of decision-making tasks. To achieve this, we utilized a self-developed League of Legends Risk Propensity Scale (LRPS) to characterize LOL players' in-game risk preferences.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!