AI Article Synopsis
- Favre-Racouchot disease (FRD) is a benign occupational disorder caused by chronic UV exposure, primarily affecting elderly men with light skin, leading to skin changes around the eyes and temples.
- While FRD is associated with solar elastosis and comedonal lesions, it surprisingly shows a reduced incidence of malignant skin cancers, indicating a potential protective factor within the condition.
- The text reviews the clinical features, causes, and treatment options for FRD, highlighting the need to understand elastosis as a potentially beneficial response of the skin.
Article Abstract
Favre-Racouchot disease (FRD) is an occupational disorder characterized by solar elastosis with open and cystically dilated comedones that tend to appear on the periorbital and temporal face of elderly light-complexioned men. It is a benign condition caused by chronic excessive ultraviolet exposure, as well as ionizing radiation and/or smoking. However, malignant skin neoplasms are uncommonly observed arising in FRD, which suggests a protective role of some element of FRD against carcinogenesis. We explore elastosis as a possibly beneficial tissue response. The clinical manifestations, pathogenesis, and recommended treatment options of this disorder are reviewed.
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| http://dx.doi.org/10.1007/s00403-021-02202-5 | DOI Listing |
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