Objectives: The aim of the study was to examine a secular trend in age at menarche (AAM) in the former Czechoslovak (and descendant Slovak and Czech) population in relation to its large-scale political and social events taking place after World War II.
Methods: The study included 211 women aged 18-30 (born during 1984-1998), and their relatives: mothers, sisters, and grandmothers, yielding a total of 421 women. Changes in retrospectively recalled AAM between the three generations of women (oldest-grandmothers, middle-mothers, and youngest-daughters) were studied in pairwise comparisons. Relationships between AAM and the birth/conception date were analyzed relative to three events in the post-WWII Czechoslovakia (1948, 1968, and 1989).
Results: AAM was the highest in the oldest generation, slightly lower in the middle generation and the lowest in the youngest generation. Mixed-Effect Model showed statistically significant interaction between the date of conception, historical events, and the period before and after the event.
Conclusions: The recorded decline in AAM is congruent with secular trends reported in the literature. However, the decreasing trend was not linear and included an increase in AAM in women conceived within the five-year period after the invasion of Czechoslovakia by communist armies in 1968.
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http://dx.doi.org/10.1002/ajhb.23588 | DOI Listing |
BMC Endocr Disord
January 2025
Faculty of Medicine and Health Sciences, Department of Obstetrics and Gynaecology, University of Zimbabwe, P. O. Box A178, Avondale, Harare, Zimbabwe.
Background: Proper planning of reproductive health needs for HIV-infected adolescents requires a clear understanding of the effects of HIV infection on adolescents' pubertal development.
Objective: To assess the effects of HIV infection on the hypothalamic-pituitary-ovarian (HPO) axis, ovarian reserve and pubertal development in adolescent girls at a tertiary hospital in Zimbabwe.
Methods: This was a cross-sectional survey of HIV-infected adolescent girls aged 10-19 years, with available CD4 + count results at a tertiary hospital in Zimbabwe.
Menopause
January 2025
Department of Child, Family, and Population Health Nursing, University of Washington, Seattle, WA.
Objective: This study aimed to determine whether exposure to traffic-related air pollution (TRAP) is associated with depressive symptoms while also characterizing the contribution of key explanatory factors related to sociodemographics and health. In addition, it aimed to also explore the role of reproductive health as a pathway through which exposure to TRAP may relate to depressive symptoms.
Methods: Participants were 688 healthy reproductive-age women in the Ovarian Aging Study.
Cancer Res Commun
January 2025
University Hospitals Leuven, Leuven, Belgium.
This study evaluated the association between age at first full-term pregnancy (FFTP) and mammographic breast density (MBD) in postmenopausal women. 1,034 women, age 50-69y, were recruited from the Flemish (Belgium) population-based breast cancer screening program. Participants completed a questionnaire on lifestyle and reproductive factors.
View Article and Find Full Text PDFJ Reprod Infertil
January 2024
Departments of Anatomy and Physiology, Edo State University Uzairue, Auchi, Nigeria.
The impact of artificial light exposure on human health has garnered significant attention in recent years. In particular, its effects on reproductive health have raised concerns. Given that the onset of menarche serves as a crucial indicator of reproductive maturity, understanding the implications of artificial light exposure becomes paramount.
View Article and Find Full Text PDFInt J Fertil Steril
January 2025
Jubilee Centre for Medical Research, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India. Email:
Background: Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine conditions that significantly impact the life quality of reproductive-aged women. In the Indian population, its prevalence varies from 3.7 to 22.
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