AI Article Synopsis

  • In December 2019, a viral pneumonia outbreak in Wuhan, China led to the identification of a novel coronavirus as the cause.
  • Due to its rapid human-to-human transmission, COVID-19 quickly escalated to an epidemic and was declared a public health emergency by the WHO.
  • The review seeks to summarize recent research on COVID-19's molecular characteristics and immune responses to aid further studies on prevention and treatment strategies for SARS-CoV-2, drawing insights from past research on SARS-CoV and MERS-CoV.

Article Abstract

In late December 2019, a vtiral pneumonia with an unknown agent was reported in Wuhan, China. A novel coronavirus was identified as the causative agent. Because of the human-to-human transmission and rapid spread; coronavirus disease 2019 (COVID-19) has rapidly increased to an epidemic scale and poses a severe threat to human health; it has been declared a public health emergency of international concern (PHEIC) by the World Health Organization (WHO). This review aims to summarize the recent research progress of COVID-19 molecular features and immunopathogenesis to provide a reference for further research in prevention and treatment of SARS coronavirus2 (SARS-CoV-2) infection based on the knowledge from researches on SARS-CoV and Middle East respiratory syndrome-related coronavirus (MERS-CoV).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904902PMC
http://dx.doi.org/10.3389/fcimb.2021.563085DOI Listing

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