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Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research.
Mol Psychiatry
December 2024
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Psychiatric disorders are highly comorbid, heritable, and genetically correlated [1-4]. The primary objective of cross-disorder psychiatric genetics research is to identify and characterize both the shared genetic factors that contribute to convergent disease etiologies and the unique genetic factors that distinguish between disorders [4, 5]. This information can illuminate the biological mechanisms underlying comorbid presentations of psychopathology, improve nosology and prediction of illness risk and trajectories, and aid the development of more effective and targeted interventions.
View Article and Find Full Text PDFConsidering the interconnected nature of social identities in neuroimaging research.
Nat Neurosci
December 2024
Department of Psychiatry, Brain Health Institute, Rutgers University, Piscataway, NJ, USA.
Considerable heterogeneity exists in the expression of complex human behaviors across the cognitive, personality and mental health domains. It is increasingly evident that individual variability in behavioral expression is substantially affected by sociodemographic factors that often interact with life experiences. Here, we formally address the urgent need to incorporate intersectional identities in neuroimaging studies of behavior, with a focus on research in mental health.
View Article and Find Full Text PDFEvaluating data sharing statements in leading emergency medicine journals: A mixed methods review.
Am J Emerg Med
December 2024
Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, United States; Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, OK, United States.
Background: Emergency medicine remains as the front line of healthcare, providing acute care to a diverse population during urgent and critical moments. Our objective was to systematically quantify the prevalence of data sharing statements (DSS) in high-impact emergency medicine journals and assess their implementation by contacting corresponding authors who indicated data available upon request.
Methods: We conducted a cross-sectional analysis to identify the prevalence and content of data sharing statements in clinical studies published in high impact emergency medicine journals between 2018 and 2023, followed by a hierarchical logistic regression analysis to identify variables impacting the incorporation of data sharing statements into emergency medicine studies.
Annual Research Review: How did COVID-19 affect young children's language environment and language development? A scoping review.
J Child Psychol Psychiatry
December 2024
Centre for Psychological Research, Oxford Brookes University, Oxford, UK.
A diverse body of research conducted since the start of Covid-19 has investigated the impact of the pandemic on children's environments and their language development. This scoping review synthesises the peer-reviewed research literature on this topic between 2020 and 2023. Following the Joanna Briggs Institute methodology and the PRISMA extension for scoping reviews, we searched five databases for studies that fulfilled the following inclusion criteria: studies with neurotypical (monolingual or multilingual) 0-6-year-old children; studies focusing on any area of language development, including sources describing literacy or educational practices that impacted language development; studies focusing in the context of the COVID-19 pandemic, with no restrictions of geographical location or language used by participants.
View Article and Find Full Text PDFComparing the predictive validity of four MCI definitions for incident dementia in demographically diverse community-dwelling individuals: Results from the Einstein Aging Study (EAS).
J Int Neuropsychol Soc
December 2024
Department of Psychology, Queens College, City University of New York (CUNY), Flushing, NY, USA.
Objective: Research examining (MCI) criteria in diverse and/or health-disparate populations is limited. There is a critical need to investigate the predictive validity for incident dementia of widely used MCI definitions in diverse populations.
Method: Eligible participants were non-Hispanic White or Black Bronx community residents, free of dementia at enrollment, with at least one annual follow-up visit after baseline.
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