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The birth of rhinoplasty in the West was driven by a great demand for reconstruction of noses destroyed voluntarily or not, post-traumatic or medical. Two men emerge strongly through their work and writings: Gaspare Tagliacozzi for the brachial flap and Joseph Carpue for the frontal flap. Both of them describe a different method but based on the same skin flap principles. But were they really the first? History tells us that other, more anonymous people before them had used these same methods on a large scale but without leaving any conclusive or very significant written trace. The use of flaps or grafts, methods, which are the true pillars of plastic surgery, opened up perspectives much wider than the nose. But history has retained the name of these two men through their writings. If they were not the precursors, they were nevertheless promoters, laying the foundations of modern plastic surgery and promoting the spread of these great principles throughout the world.
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http://dx.doi.org/10.1016/j.anplas.2021.01.002 | DOI Listing |
Pak J Pharm Sci
March 2025
Department of Plastic and Cosmetic Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
To compare the drug effects and adverse reactions of doxycycline and isotretinoin in patients with moderate to severe acne. A retrospective analysis was conducted on 98 patients with moderate to severe acne who were treated in the Affiliated Hospital of Nanjing University of Traditional Chinese Medicine from June 2020 to June 2023. They were divided into group A and group B based on actual medication use, with 49 cases in each group.
View Article and Find Full Text PDFWorld J Surg Oncol
March 2025
Department of Plastic and Reconstructive Surgery, Inje University Busan Paik Hospital, Inje University College of Medicine, 75 Bokji-ro, Busanjin-gu, Busan, 47392, Republic of Korea.
Background: This study analyzes the aesthetic outcomes associated with inframammary fold (IMF) incisions compared to radial incisions, with or without a periareolar component (referred to as periareolar/radial, PR), considering nipple-sparing mastectomy (NSM) followed by prepectoral direct-to-implant (DTI) reconstruction and subsequent post-mastectomy radiotherapy (PMRT). We assessed changes in breast and nipple symmetry, nipple-to-IMF distance, and nipple Y-axis coefficients to understand how different incisions influence post-radiation aesthetic outcomes.
Methods: Forty patients who underwent NSM and prepectoral DTI reconstruction followed by PMRT between September 2019 and December 2022 in a single institution were included.
Discov Oncol
March 2025
The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, BaYi Road No. 463, DongHu District, NanChang, 330006, Jiangxi, China.
Objective: This study aimed to investigate the causal relationship between inflammatory cytokines and oral cavity cancer risk using Mendelian randomization analysis and experimental validation.
Methods: Two-sample Mendelian randomization was conducted using summary-level genome-wide association study data on 41 inflammatory cytokines and oral cavity cancer risk in Europeans. Single nucleotide polymorphisms associated with cytokines (p < 5 × 10-6) and oral cancer were selected as instrumental variables, excluding those in linkage disequilibrium.
Surv Ophthalmol
March 2025
Corneoplastic Unit, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, United Kingdom.
Dynamic reconstructive techniques of the eyelid in facial nerve palsy aim to restore or replace spontaneous and voluntary movement. These may include transfer and graft techniques of nerve and muscle. The role of these procedures from an ophthalmic and oculoplastic perspective is yet to be established.
View Article and Find Full Text PDFBurns
February 2025
Amalia Centre of Expertise Pediatric Trauma and Burns, Radboud University Medical Centre, Nijmegen, the Netherlands; Department of Plastic, Reconstructive and Hand Surgery, Radboud University Medical Centre, Nijmegen, the Netherlands.
Superficial partial thickness burns typically receive nonoperative treatment, whereas deep partial thickness burns, which are prone to hypertrophic scarring, are usually managed through debridement followed by autologous split-thickness skin grafting. Various therapies have been developed to prevent wound infection and to enhance wound healing in pediatric partial-thickness burns. However, the choice of dressing by the surgeon can be influenced by various factors.
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