AI Article Synopsis

  • The study focused on analyzing pediatric patients in Bogotá who had urinary tract infections (UTIs) caused by community-acquired extended-spectrum b-lactamase (ESBL)-producing enterobacteriaceae from their first urine cultures.
  • Over a six-year period, 2657 positive urine cultures were reviewed, and data from 132 patients were specifically analyzed, revealing a 5% frequency of ESBL-producing bacteria in these UTIs.
  • The findings indicated that most affected patients were preschool-aged females and that the infections were primarily in the lower urinary tract, with the bacteria showing good sensitivity to amikacin and nitrofurantoin.

Article Abstract

Objective: To characterize the pediatric patients presenting at the two pediatric centers in Bogotá, with first isolate urine culture of community-acquired extended-spectrum b-lactamase (ESBL)-producing enterobacteriaceae.

Methods: Review of microbiological data of children between January, 2012 and December, 2018, obtained using the WHONET software.

Results: A total of 2657 Escherichia coli, Klebsiella spp and Proteus mirabilis - positive urine cultures were obtained within a 6-year period; data of 132 patients were finally selected. Frequency of ESBL-producing bacteria infections in community-acquired urinary tract infections (UTI) was 5%: 123 E. coli (93.2%), 7 K. pneumoniae (5.2%), 1 K. oxytoca (0.8%), and 1 P. mirabilis (0.8%).

Conclusion: A predominance of female sex, preschool children, and lower tract urinary infections were found, as well as a low frequency of comorbidities. Adequate sensitivity to amikacin and nitrofurantoin was found in this study.

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