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http://dx.doi.org/10.1111/ans.16689 | DOI Listing |
spores are essential for initiation, recurrence and transmission of the disease. The spore surface layers are composed of an outermost exosporium layer that surrounds another proteinaceous layer, the spore coat. These spore surfaces layers are responsible for initial interactions with the host and spore resistance properties contributing to transmission and recurrence of CDI.
View Article and Find Full Text PDFExpert Rev Gastroenterol Hepatol
January 2025
Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of California San Diego, San Diego, CA.
Introduction: The gut microbiota has a complex relationship with the human host and is key to maintaining health. Disruption of the healthy diverse gut microbial milieu plays an important role in the pathogenesis of several diseases including infection (CDI), inflammatory bowel disease, irritable bowel syndrome, alcohol-related liver disease and metabolic-dysfunction associated steatotic liver disease (MASLD). Fecal microbiota transplantation (FMT) is highly effective in treating CDI, though its utility in other diseases is still being explored.
View Article and Find Full Text PDFBackground infection (CDI) is a significant healthcare concern, marked by its rising prevalence and associated morbidity and mortality. However, there is limited data on the epidemiology of CDI in the eastern region of India. Objectives The study aims to determine the incidence of CDI among adult patients admitted to the inpatient department of a tertiary care hospital and identify the risk factors associated with CDI.
View Article and Find Full Text PDFLancet Reg Health Eur
February 2025
Infectious Disease Service, Fondazione Policlinico Universitario Campus Bio-Medico, 00127, Rome, Italy.
Antimicrob Steward Healthc Epidemiol
December 2024
Departments of Medicine and Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Objective: To estimate incidence and healthcare costs and mortality associated with infection (CDI) among adults <65 years old.
Design: Retrospective cohort study.
Patients: First CDI episodes among commercially insured US patients 18-64 years old were identified from a large claims database.
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