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Overexpression of SikPsaF can increase the biomass of Broussonetia papyrifera by improving its photosynthetic efficiency and cold tolerance.
Plant Sci
January 2025
College of Life Science, Shihezi University, Shihezi 832000, PR China. Electronic address:
Photosynthesis is essential for the accumulation of organic compounds in plant leaves. Study of photosynthesis in the leaves of Broussonetia papyrifera is crucial for enhancing its biomass production, growth, and development. Here, we cloned the SikPsaF gene associated with photosynthesis from Saussurea involucrata and constructed a vector that was introduced into B.
View Article and Find Full Text PDFEntry into the lytic cycle exposes EBV-infected cells to NK cell killing via upregulation of the MICB ligand for NKG2D and activation of the CD56 and NKG2AKIRCD56 subsets.
Front Immunol
December 2024
Research Unit of Primary Immunodeficiency, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
The Epstein-Barr virus (EBV) is usually acquired during infancy as an asymptomatic infection and persists throughout life in a latent state under the control of the host immune system. However, EBV is associated with various malignant diseases that preferentially develop in immunodeficient individuals. Accumulating evidence suggests an important role for NK cells, though the mechanisms by which EBV evades or triggers NK cell responses are poorly understood.
View Article and Find Full Text PDFCorneal application of SOCS1/3 peptides for the treatment of eye diseases mediated by inflammation and oxidative stress.
Front Immunol
August 2024
Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, United States.
Several blinding diseases affecting the retina and optic nerve are exacerbated by or caused by dysregulated inflammation and oxidative stress. These diseases include uveitis, age related macular degeneration, diabetic retinopathy and glaucoma. Consequently, despite their divergent symptoms, treatments that reduce oxidative stress and suppress inflammation may be therapeutic.
View Article and Find Full Text PDFConformational Alterations of the Cell Surface of Monomeric and Dimeric β2m-Free HLA-I (Proto-HLA) May Enable Novel Immune Functions in Health and Disease.
Curr Issues Mol Biol
July 2024
Division of Nephrology, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19145, USA.
Human leukocyte antigens (HLAs) are polymorphic glycoproteins expressed on the cell surface of nucleated cells and consist of two classes, HLA class I and HLA class II. In contrast, in mice, these molecules, known as H-2, are expressed on both nucleated cells and erythrocytes. HLA-I molecules (Face-1) are heterodimers consisting of a polypeptide heavy chain (HC) and a light chain, B2-microglobulin (B2m).
View Article and Find Full Text PDFThe dynamics of the electrotactic reaction of mouse 3T3 fibroblasts.
Biochim Biophys Acta Mol Cell Res
February 2024
Jagiellonian University, Faculty of Biochemistry, Biophysics and Biotechnology, Department of Cell Biology, Gronostajowa 7, 30-387 Kraków, Poland. Electronic address:
The molecular mechanisms behind electrotaxis remain largely unknown, with no identified primary direct current electric field (dcEF) sensor. Two leading hypotheses propose mechanisms involving the redistribution of charged components in the cell membrane (driven by electrophoresis or electroosmosis) and the asymmetric activation of ion channels. To investigate these mechanisms, we studied the dynamics of electrotactic behaviour of mouse 3T3 fibroblasts.
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