Objective: This study was done to evaluate the and effects of the essential oil (OE-CL) and nanoemulsion (N-CL) of against
Materials And Methods: assays were done with 10 parasites and OE-CL and N-CL in the concentrations: 110, 220, 330, 440, 550, 660, 770 and 880 µg/ml and four controls: CN (culture medium and trophozoites), MTZ (trophozoites plus 800 µg/ml of metronidazole), TW (trophozoites plus vehicles used for solubilization of derivatives (0.01% Tween) and NB (blank nanoemulsion 880 µg/ml). The assay was done in 35 quails () infected experimentally 4x10 mg/kg, were divided in seven groups (n=5): A (control-healthy), B (control infected), C (control TW 0.01%), D (NB 0.88 mg/kg), E (drug MTZ 25 mg/kg, F (OE-CL at 0.55 mg/kg) and G (N-CL at 0.44 mg/kg), during 7 consecutive days.
Results: The test showed that the OE-CL (550 μg/ml) and N-CL (440 μg/ml) concentrations reduced the trophozoites viability in 100%. In the test, the treatment with OE-CL was efficient on the 4 treatment day and the N-CL after the 3 day, and the MTZ in the therapeutic concentration was efficient on the 7 day.
Conclusion: It can be observed in this study that the lemon grass has natural potential antitrichomonal activity against and .
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Source |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885001 | PMC |
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