Emerging cases of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) have been associated with a variety of disorders including respiratory failure, immune reactive syndrome, multiorgan failure, and hypercoagulable states. COVID-19 induces a severe global inflammatory response which can result in endothelial damage leading to hypercoagulability. Most COVID-19 cases of hypercoagulable states reported venous thrombosis. We report here a case of a 65-year-old Hispanic male diagnosed with bilateral acute lower limb ischemia and renal infarcts secondary to a severe COVID-19 infection.
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http://dx.doi.org/10.7759/cureus.12784 | DOI Listing |
BMJ Open
December 2024
Institute for Musculoskeletal Health, Sydney Local Health District, Sydney, New South Wales, Australia.
Introduction: Sciatica is a debilitating condition that often becomes chronic, and for which there are few effective treatment options. Treatments such as the anti-depressant duloxetine have shown promise, but the evidence is inconclusive. We are describing a high quality, definitive trial to investigate the efficacy, safety and cost-effectiveness of duloxetine in chronic sciatica.
View Article and Find Full Text PDFIn Vivo
December 2024
Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Background/aim: The incidence and characteristics of pediatric thrombotic events have become increasingly recognized, due to the enhanced utilization of advanced diagnostic techniques. Pediatric thrombosis remains less frequent than in adults, often manifesting in those with underlying congenital or acquired risk factors. This study aimed to establish epidemiological data on pediatric thrombotic events in Bihor County, Romania, highlighting the challenges of diagnosis in smaller medical centers and proposing a relevant diagnostic and treatment algorithm.
View Article and Find Full Text PDFClin Biomech (Bristol)
December 2024
Department of Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.
Background: Grip Strength has been established as a practical and efficient method for screening and diagnosing sarcopenia. It is recognized that with advancing age, there is a more significant decline in lower limb muscle mass compared to the upper limb. However, due to the inherent complexity of assessing lower limb muscle strength compared to measuring Grip Strength, these assessments have not been universally adopted for sarcopenia screening.
View Article and Find Full Text PDFMusculoskelet Sci Pract
December 2024
Department of Mathematics, Massey University, East Precinct Albany Expressway, SH17, Albany, Auckland, 0632, New Zealand.
Objectives: To describe a rapid, community-based assessment, referral and management system for acute symptomatic LDH. To identify and describe specific local anaesthetic and corticosteroid patterns of pain intensity change during the first week post-epidural injection.
Setting: Private practice, specialist physiotherapy clinic, community-based radiology facility.
Int J Surg Case Rep
December 2024
Department of Vascular Surgery, Faculty of Medicine, Aleppo University Hospital, University of Aleppo, Aleppo, Syria.
Introduction And Importance: Leriche syndrome (LS), or aortoiliac occlusive disease, is a rare form of peripheral arterial disease leading to claudication, impotence, and diminished femoral pulses due to atheromatous obstruction of the infrarenal aorta and common iliac arteries. Early identification is crucial as untreated LS can result in severe complications. Treatment primarily involves surgical interventions, with endovascular options considered as alternatives.
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