Objective: This study aimed to examine the effectiveness of ozonated oil on the wound healing response of full-thickness defect tissue in Sprague-Dawley rats, assessed by collagen thickness and the number of fibroblasts.
Methods: This was an experimental research method using control groups and treatment groups with a posttest only control group design. The results showed that collagen thickness in wounds tended to increase, assessed on day 3 and day 7 using Masson's trichrome staining and microscopic evaluation.
Results: There was a significant difference in the number of fibroblasts between the two control and treatment groups on days 3 and 7 tested using one-way Kruskal-Wallis test, with a value of =0.001( < 0.05), resulting in a significant difference in wound size reduction between the groups. Further post hoc analysis using the Mann-Whitney test indicated a significant difference between the control groups and the treatment groups (P0, P1 versus P3, P4, P5, P8, P9, and P10) with a value of =0.009( < 0.05).
Conclusions: Ozonated oil is effective in increasing the healing response of full-thickness defects, leading to the increase in the number of fibroblasts and collagen thickening that in turn accelerates wound healing in Sprague-Dawley rats.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7886587 | PMC |
| http://dx.doi.org/10.1155/2021/6654343 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Is There an Ideal Concentration of Ozonized Oil for the Prevention and Modulation of Zoledronate-Induced Mandibular Osteonecrosis? A Study on Senescent Rats.
J Funct Biomater
November 2024
Department of Oral Diagnosis, Division of Oral and Maxillofacial Surgery, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba 13414-903, Sao Paulo, Brazil.
This study aimed to identify whether there is an ideal concentration for applying ozonized oil (OZ) in the post-exodontic alveoli of senescent rats treated with zoledronate (ZOL). Thirty-five female rats, aged 18 months, were divided into five groups: ZOL; ZOL+OZ500; ZOL+OZ600; ZOL+OZ700; and SAL. The groups treated with ZOL, and other concentrations of OZ received applications at a dose of 100 μg/kg, while the SAL group received saline.
View Article and Find Full Text PDFInfluence of ozone treatment on sensory quality, aroma active compounds, phytosterols and phytosterol oxidation products in stored rapeseed and flaxseed oils.
Food Chem
December 2024
Faculty of Food Science and Nutrition, Poznań University of Life Sciences, Wojska Polskiego 31, 60-624 Poznań, Poland.
The effect of ozone treatment on the sensory quality, aroma compounds, phytosterols, and phytosterol oxidation products (POP) in stored plant oils was studied. Cold-pressed flaxseed, cold-pressed rapeseed, and refined rapeseed oils were treated with ozone, air, and nitrogen, then subjected to accelerated storage at 60 °C for 6 days. The sensory evaluation revealed that ozone significantly influenced the sensory profile, with notable cucumber and green-grassy aromas.
View Article and Find Full Text PDFAssessment of atmospheric volatile organic compounds at two crude oil production plants in Southeastern Türkiye.
Environ Monit Assess
December 2024
Graduate School of Natural and Applied Sciences, Gazi University, Ankara, 06500, Türkiye.
Ambient Volatile Organic Compounds (VOCs) were investigated to determine their characteristics, Ozone Formation Potentials (OFPs), and health risks in two crude oil production plants (Nusaybin and Egil plants) in southeastern Türkiye. Benzene, toluene, ethylbenzene, m + p xylene, o xylene, and 1,3,5-trimethylbenzene were measured at eight passive sampling points in each plant. Samples were analyzed using gas chromatography coupled with a flame ionization detector and a thermal desorption.
View Article and Find Full Text PDFThe potential role and limitations of antiseptic eyedrops in ophthalmic surgery.
Eur J Ophthalmol
December 2024
Department of Medicine - Ophthalmology, University of Udine, Udine, Italy.
Purpose: the aim of the present study is to analyse the composition of the currently available topical antiseptic products and the related scientific evidence, and to discuss the implications of their use in the prevention of endophthtalmitis.
Methods: products available on the market until February 2024 were considered. Information provided on the illustration leaflet of each product were analysed.
Investigation of Mechanical Properties and Oil Resistance of Hydrogenated-Butadiene-Acrylonitrile-Rubber-Based Composites Across Various Temperatures.
Polymers (Basel)
November 2024
Institute of New Electrical Material, China Electric Power Research Institute Co., Ltd., Beijing 100192, China.
The influence of molecular structure (acrylonitrile content) and formulation (carbon black and plasticizer dosage) on the rheological and mechanical properties of HNBR composites was systematically studied, with further discussion on ozone resistance and swelling behavior in transformer oil. The results demonstrated that the curing characteristics and rheological behavior of HNBR composites are closely linked to acrylonitrile content, carbon black, and plasticizer levels. Plasticizers significantly reduced the degree of crosslinking and the Payne effect, while fillers had the opposite impact.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!