In this study, an analytical method for the simultaneous determination of the novel insecticide flupyradifurone and its two metabolites in a variety of traditional Chinese herbal medicines was developed for the first time using high-performance liquid chromatography-tandem mass spectrometry. A simple and efficient method using dispersive solid-phase extraction was employed for the pretreatment of the samples. Several extractions and cleanup strategies were evaluated. The recoveries ( = 15) of flupyradifurone and its metabolites at three spiking levels were in the range 71.3%-101.7%, with corresponding intraday and interday relative standard deviations of 1.1%-14.8%. The limits of quantitation were 0.01 mg/kg for flupyradifurone and 0.1 mg/kg for its two metabolites. Overall, our developed method was sensitive and reliable for the fast screening of flupyradifurone and its two metabolites in traditional Chinese herbal medicine samples.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7895605 | PMC |
| http://dx.doi.org/10.1155/2020/8812797 | DOI Listing |
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Small volume solid phase extraction method for comprehensive analysis of neonicotinoids, their metabolites, and related pesticides in water.
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