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Circadian Misalignment Impacts Cardiac Autonomic Modulation in Adolescence.
Sleep
January 2025
Sleep Research & Treatment Center, Department of Psychiatry & Behavioral Health, Penn State University, College of Medicine, Hershey PA, USA.
Study Objectives: Although heart rate variability (HRV), a marker of cardiac autonomic modulation (CAM), is known to predict cardiovascular morbidity, the circadian timing of sleep (CTS) is also involved in autonomic modulation. We examined whether circadian misalignment is associated with blunted HRV in adolescents as a function of entrainment to school or on-breaks.
Methods: We evaluated 360 subjects from the Penn State Child Cohort (median 16y) who had at least 3-night at-home actigraphy (ACT), in-lab 9-h polysomnography (PSG) and 24-h Holter-monitoring heart rate variability (HRV) data.
Cortical windows for implant and cement removal during revision total elbow arthroplasty.
JSES Int
November 2024
Division of Hand and Upper-Extremity Surgery, Department of Orthopaedic Surgery, Geisinger Commonwealth School of Medicine, Geisinger MSKI, Danville, PA, USA.
Background: Revision total elbow arthroplasty (rTEA) remains a technically challenging procedure with potential for substantial morbidity. Cases involving excessively long cement mantles, removal of well-fixed implants or infected revisions requiring complete cement removal introduce additional technical challenges. Our purpose was to describe the outcomes, results, and complications associated with the use of cortical windows in rTEA.
View Article and Find Full Text PDFBifrontal Craniectomy: A High-Yield Surgical Training Tool.
Cureus
December 2024
Department of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, USA.
Bifrontal decompressive craniectomy (DC), which was once a popular technique for treating midline mass lesions, has seen a notable decline in its therapeutic use within modern neurosurgery. Despite its diminished clinical use, the procedure offers considerable value as an educational tool for surgical training. This study used a Thiel-embalmed cadaver to demonstrate the bifrontal DC procedure, including a Souttar incision, strategic (MacCarty, zygomatic, and apical) keyhole/burr hole placement, superior sagittal sinus suturing, left frontal lobe decortication, and microscopic visualization of the anterior cranial fossa.
View Article and Find Full Text PDFPhysiology of Pacing Symposium 2024: Letter from the Program Directors.
J Innov Card Rhythm Manag
December 2024
Arizona College of Medicine, Banner Health, Phoenix, AZ, USA.
Transforming pharmacology education: Insights from the pharmacology education project in the era of digital learning.
Eur J Pharmacol
January 2025
Internal Medicine Office, Medical Education Centre, Western General Hospital, Edinburgh, EH4 2XU, UK. Electronic address:
The IUPHAR Education Section's Pharmacology Education Project (PEP; www.pharmacologyeducation.org) provides an open-access, peer-reviewed platform to support pharmacology education globally.
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