AI Article Synopsis
- A 79-year-old woman was hospitalized with symptoms like dizziness, headache, jaw pain, and visual disturbances, suspected to have giant cell arteritis (GCA).
- Her examination showed significantly enlarged and tender superficial temporal arteries, along with high eosinophil levels and positive myeloperoxidase-ANCA results.
- A biopsy confirmed granulomatous inflammation, leading to the conclusion that her GCA was the first indication of eosinophilic granulomatosis with polyangiitis (EGPA), marking it as a unique case in medical literature.
Article Abstract
A 79-year-old woman was admitted for suspected giant cell arteritis (GCA). She had suffered from dizziness, headache, jaw claudication and visual disturbance. Her medical history included bronchial asthma and parasinusitis. Her superficial temporal arteries were markedly enlarged with tenderness. Laboratory data showed eosinophilia (6968/µL) and a positive result of myeloperoxidase-ANCA. A histological examination of the biopsied artery revealed granulomatous inflammation consisting of lymphocytes and eosinophils with a multinucleated giant cell. Her conditions met both the criteria for GCA and eosinophilic granulomatosis with polyangiitis (EGPA). We finally considered that she had temporal arteritis as an initial manifestation of EGPA after a comprehensive literature review. To our knowledge, this is the first case in which temporal arteritis with a giant cell developed as an initial and sole manifestation of EGPA.
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| http://dx.doi.org/10.1080/24725625.2021.1893944 | DOI Listing |
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