Objective: Parkinson's disease (PD) is a neurodegenerative disorder. It has a significant impact on the quality of life of patients and their caregivers. The present study aims to study the phenomena of neuropsychiatric symptoms and their association with caregiver burden in PD.
Methods: The study was conducted in 100 patients of Parkinson's disease and their primary caregivers. The patients of PD were diagnosed on the basis of UK Brain Bank criteria; severity/staging of Parkinson's disease was done by Movement Disorder Society - Unified Parkinson's disease rating scale (MDS-UPDRS-III). Patients who fulfilled inclusion and exclusion criteria were recruited for the study. The neuropsychiatric evaluation was based on Neuropsychiatric Inventory-Questionnaire (NPI-Q). Caregiver burden was assessed with the Zarit Caregiver Burden Inventory (ZCBI).
Results: Mean age of PD patients was 61.48 ± 6.71 years, majority of them were males (68%). Mean total NPI score of patients was 44.46 ± 5.38. Mean age of caregivers was 52.26 ± 6.80 years, majority of them were females (72%) and spouse (76%) in relation to the patient. Caregiver burden was significantly related to age of the patient, duration of illness, severity of illness, and total NPI score.
Conclusion: Neuropsychiatric symptoms significantly contribute to the caregiver burden in Parkinson's disease.
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http://dx.doi.org/10.4103/aian.AIAN_91_20 | DOI Listing |
Cureus
February 2025
Psychiatry, Bundelkhand Medical College, Sagar, IND.
The study highlights six cases in which obsessive-compulsive disorder (OCD) in a primary patient was recognized through distress or behavioral changes in a family member. Common themes included compulsive behaviors that led to physical and emotional strain on relatives, leading them to seek medical attention. This underscores the indirect impact of OCD on family members, emphasizing the bio-psycho-social interplay in symptom manifestation and caregiving dynamics.
View Article and Find Full Text PDFCancer
March 2025
Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.
J Neurol
March 2025
Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari 'Aldo Moro', "Pia Fondazione Cardinale G. Panico", Via San Pio X, 73039, Tricase, Lecce, Italy.
Background: Fatigue is a common non-motor symptom (NMS) in Parkinson's disease (PD), affecting up to 50% of patients. It is suggested that PD-related fatigue may contribute to the burden perceived by caregivers.
Objective: This study aims to evaluate the impact of PD-related fatigue on caregiver burden.
J Neurol
March 2025
Computational Neuroimaging Group (CNG), School of Medicine, Trinity College, Pearse Street, Dublin, Ireland.
Background: Pseudobulbar affect (PBA) is a well-recognised and troublesome clinical phenomenon in a range of neuroinflammatory, neoplastic, neurovascular and neurodegenerative conditions. It is often under-recognised in the community, frequently mistaken for psychiatric manifestations, appropriate pharmacological treatment is often delayed, and may result in a sense of embarrassment or lead to social isolation. Despite its considerable quality of life (QoL) implications and the challenges associated with its effective management, it is notoriously understudied.
View Article and Find Full Text PDFDisabil Rehabil
March 2025
Center for Interdisciplinary Research in Rehabilitation and Social Integration (Cirris), Centre Intégré Universitaire de Santé et de Services Sociaux de la Capitale Nationale (CIUSSS-CN), Quebec City, Canada.
Purpose: In Sub-Saharan Africa, family caregivers (FCs) almost systematically-and sometimes indefinitely-assist stroke survivors with activities of daily living and the stroke rehabilitation process. This study explored the experiences of FCs of stroke survivors in Burkina Faso.
Materials And Methods: A descriptive qualitative study was conducted with FCs recruited through convenience sampling.
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