Objective: To estimate levels of early childhood develop-ment (ECD) and associated factors in Mexican population aged 19-59 months.
Materials And Methods: The Ensanut 2018-19 evaluated ECD using the Early Childhood Development Index (ECDI) and level of language develop-ment. We used multivariate models, with logistic or linear regression, depending on the outcome variable.
Results: Children of wealthier households and with children's books at home are more likely of having an adequate ECDI; in contrast, children who experienced violent discipline methods are less likely. Children living in rural areas, with more highly educated mothers, who were not undernourished, and with support for learning have higher language scores.
Conclusions: Public policies aimed to enhance early childhood development should take into account the associated modifiable factors.
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http://dx.doi.org/10.21149/11869 | DOI Listing |
JAMA Netw Open
January 2025
Department of Health Policy and Management, Yale School of Public Health, New Haven, Connecticut.
Importance: Disparities in cognition, including dementia occurrence, persist between non-Hispanic Black (hereinafter, Black) and non-Hispanic White (hereinafter, White) older adults, and are possibly influenced by early educational differences stemming from structural racism. However, the association between school racial segregation and later-life cognition remains underexplored.
Objective: To investigate the association between childhood contextual exposure to school racial segregation and cognitive outcomes in later life.
Alzheimers Dement
December 2024
Universidade do Vale do Rio dos Sinos, São Leopoldo, Rio Grande do Sul, Brazil.
Background: In recent years, researchers have linked epigenetic factors to numerous diseases, one of them being Alzheimer's Disease (AD). Those factors may lead to the disease but also serve as a path for new treatments and prevention methods.
Method: A wide selection of articles in the PubMed platform that focused on epigenetics, Alzheimer's Disease, and correlating aspects among them were reviewed.
Alzheimers Dement
December 2024
Memory and Aging Center, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Background: Emerging research suggests adverse childhood experiences (ACEs) have long-lasting impacts on adult brain health, but few studies investigate these effects in older adults. The present study examined ACEs and their relationships to late-life cognitive and mental health among older adults living in the San Francisco Bay Area.
Method: 102 cognitively unimpaired older adults [mean age = 75, 58% female, 75% White, 25% Latino, mean education = 17 years] were enrolled in UC San Francisco's Alzheimer's Disease Research Center.
Alzheimers Dement
December 2024
University of Virginia, Charlottesville, VA, USA.
Background: DNA methylation (DNAm) age measures, or 'epigenetic clocks', surpass chronological age in their ability to predict age-related morbidities and mortality. The Louisville Twin Study (LTS) presents an opportunity to clarify the role of early life environmental exposures and development in biological and cognitive aging in midlife. We expect that second-generation DNAm age measures trained to predict age related outcomes and death, independent of chronological age, will be sensitive to cognitive ability in midlife.
View Article and Find Full Text PDFCurr Eye Res
January 2025
Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Purpose: To evaluate the effectiveness and safety of topical netarsudil 0.02% in managing childhood glaucoma.
Methods: A literature search in the electronic databases of PubMed CENTRAL, Google Scholar, EMBASE, the Register of Controlled Trials, and Ovid MEDLINE from January 2017 to August 2023 using one or a combination of the following terms: "netarsudil," "rhopressa," "Rho-kinase," "pediatric glaucoma," "childhood glaucoma," "intraocular pressure" was conducted.
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