Background: Nonresorbable substances are still injected to enhance soft-tissue volumes and fill subcutaneous defects. The minimally invasive intralesional laser treatment can remove foreign substances and the inflammatory reaction, eventually leaving depression and scar tissue in the treated area. Fat grafting can restore volume loss and improve scar tissue.
Methods: From March of 2010 to February of 2017, 33 patients were studied. All of them had suffered from inflammatory reactions to permanent facial fillers and had been treated with the 808-nm diode laser at the authors' institution. The evacuation of material had left facial asymmetry and visible depression. To restore facial aesthetic units, fat grafting was performed. The minimum follow-up was 6 months.
Results: Volume restoration was recognized (according to the Global Aesthetic Improvement Scale) as significantly improved in 22 patients, moderately improved in eight patients, and slightly improved in three patients. Improvement in atrophic and scarred tissues (with an apparent thickening of the skin or even elimination of scars) was also assessed with the following results: 25 patients were very much improved and eight were moderately improved.
Conclusions: This is the first study on filler-induced complications of the face treated by intralesional laser treatment followed by lipofilling. A systematic approach to volume restoration is proposed to patients who had filler removal of the face. There was a high degree of patient satisfaction with this technique.
Clinical Question/level Of Evidence: Therapeutic, IV.
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http://dx.doi.org/10.1097/PRS.0000000000007611 | DOI Listing |
J Cosmet Dermatol
March 2025
Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Background: Top surgery masculinizes the chest appearance for transgender men (TM); however, some individuals may experience hypertrophic scars (HTS) or keloids following the surgery.
Objectives: This study aimed to evaluate the efficacy of combined 595-nm pulsed dye laser (PDL) and intralesional triamcinolone acetonide injection (IL TAC) compared to IL TAC monotherapy for treating HTS and keloids.
Methods: Twenty-five TM with 35 pairs of bilateral symmetric postmastectomy HTS or keloids were randomly allocated to receive the combined PDL and IL TAC on the scar(s) on one side of the chest and IL TAC monotherapy on the contralateral scar(s) in four monthly treatment sessions.
Cureus
February 2025
Community Medicine, Maharaja Suhel Dev Autonomous State Medical College and Mahrishi Balark Hospitals, Bahraich, Bahraich, IND.
Background: Warts are benign skin growths caused by variants of human papillomavirus that infect the superficial layers of the skin and penetrate epithelial cells, causing viral multiplication. Warts can be transmitted via skin-to-skin contact and cause significant discomfort and embarrassment. There are multiple treatment options for warts, including topical therapies, cryotherapy, laser vaporization, surgical excision, and oral agents (e.
View Article and Find Full Text PDFDermatol Clin
April 2025
Department of Dermatology, University of North Carolina Chapel Hill School of Medicine, 410 Market Street Suite 400A, Chapel Hill, NC 27516, USA.
A variety of procedures may be employed for hidradenitis suppurativa, a chronic cutaneous condition that causes abscesses, nodules, and tunnels in skinfold areas. Intralesional steroid or incision and drainage are preferred for acutely inflamed discrete lesions, while deroofing or excision may be pursued for persistent or recurrent areas. Excision and deroofing may target individual lesions or complete regions that are more widely affected.
View Article and Find Full Text PDFJ Am Acad Dermatol
February 2025
Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Advancements in the treatment of keratinocyte carcinoma have broadened therapeutic opportunities for patients who elect to avoid surgery or are poor surgical candidates. Due to this evolving landscape of pharmacologic (topical, intralesional or systemic), photodynamic, laser and radiation based, and minimally-invasive treatments (either field-directed, lesion-directed, and/or systemic), providers may be faced with uncertainty in selecting an optimal alternative to surgical care. Part 2 of this CME will outline established and emerging evidence-based treatment and preventive therapies for keratinocyte carcinoma to guide care for patients with surgical contraindications.
View Article and Find Full Text PDFJ Vet Diagn Invest
February 2025
Department of Population Medicine and Diagnostic Sciences, Sections of Anatomic Pathology, Animal Health Diagnostic Center, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Virginia opossums () are the only native marsupials in the United States of America and Canada. Females have a reproductive tract consisting of a complex duplex (bifurcated) reproductive system, with 2 ovaries, 2 uteri and uterine tubes, and a vaginal complex composed of 2 lateral vaginae, vaginal sinuses, and a urogenital sinus. Few conditions of the reproductive tract have been described in these marsupials.
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