Preliminary details are given of a novel method of detecting breast lumps. The technique relies on the fact that such a lump will cause a perturbation in the pressure distribution when the breast is loaded against a flat plate. The pressure distribution is monitored by using the principle of frustrated total internal reflection to generate a brightness distribution which can then be presented as a contour map in synthesized colour. Using this technique, simulated lumps in breast prostheses have been detected down to a diameter of 6 mm. It is argued that this represents the basis of a method of mass breast screening.
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http://dx.doi.org/10.1016/0141-5425(88)90086-6 | DOI Listing |
Eur Spine J
January 2025
Exercise Intervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, Valencia, Spain.
Objective: To investigate the prospective associations between age and the risk of low back disorders (LBD), dorsal disorders (DD), and cervical disorders (CD), and to identify a potential age-threshold for increased risk of back disorders.
Methods: Prospective cohort from the UK Biobank comprising adults with no history of back disorders. We examined different ages and their association with the risk of back disorders derived from diagnoses of hospital registers.
Clin Exp Nephrol
January 2025
Reach-J Steering Committee, Tsukuba, Ibaraki, Japan.
Background: Although several studies have examined the Kidney Disease Quality of Life (KDQOL) in patients with chronic kidney disease (CKD), the factors associated with kidney-related symptoms have not been fully explored.
Methods: This nationwide multicenter cohort study enrolled 2248 patients. To identify the factors associated with each item or the three KDQOL domains, such as burden of kidney disease, symptoms/problems of kidney disease, and impact of kidney disease on daily life, multiple regression analysis was performed using baseline data.
Anal Bioanal Chem
January 2025
Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210023, China.
Insulin bound with ligand molecules can improve its bioavailability in oral formulations. In this work, the interactions between insulin and bile acids of taurocholic acid (TCA) and glycocholic acid (GCA) are characterized using different mass spectrometry (MS) methods. Electrospray (ESI)-MS analysis revealed that GCA and TCA could interact with insulin individually or together through non-covalent bonds, and the products included mGCA-insulin, nTCA-insulin, and mGCA-nTCA-insulin complexes.
View Article and Find Full Text PDFSurg Endosc
January 2025
Division of General Surgery, Bariatric Unit, Tel Aviv Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, 6, Weizman St, 6423906, Tel- Aviv, Israel.
Background: Safety in one anastomosis gastric bypass (OAGB) is judged by outcomes, but it seems reasonable to utilize best practices for safety, whose performance can be evaluated and therefore improved. We aimed to test an artificial intelligence-based model in real world for the evaluation of adherence to best practices in OAGB.Please check and confirm that the authors and their respective affiliations have been correctly identified and amend if necessary.
View Article and Find Full Text PDFPediatr Res
January 2025
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.
Background: The impact of long-term burden of body mass index (BMI) since childhood on physical performance in midlife remains unclear. We aimed to investigate the association between cumulative exposure to BMI since childhood and midlife physical performance by using data from the Bogalusa Heart Study (BHS).
Methods: This longitudinal study consisted of 749 participants (aged 37.
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