Based on an empirical analysis of video-recorded collaborative practice situations, this article looks at different ways in which a health professional can direct a request to another professional with the aim that he or she performs an action. Using a corpus of video-recorded interactions in different institutional settings and types of situations, it looks at how requests are formulated, showing that they can range from authoritative to mitigated, direct to indirect, and explicit to implicit. The study shows that professionals use a great deal of strategies to preserve politeness and each other's right not to be told what to do, aiming at mitigating the "face-threatening" aspect of requests. However, by doing so, they frequently produce unclear statements which can impede good communication and professional collaboration.
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http://dx.doi.org/10.1177/1049732321991508 | DOI Listing |
Nat Nanotechnol
January 2025
Department of Urology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Autophagosome cancer vaccines can promote cross-presentation of multiple tumour antigens and induce cross-reactive T cell responses. However, so far, there is no effective method for obtaining a highly immunogenic autophagosomal cancer vaccine because autophagosomes, once formed, quickly fuse with lysosomes and cannot easily escape from cells. Here we report a functional TiNX nanodot that caps the autophagosome membrane lipid phosphatidylinositol-4-phosphate, blocking the fusion of autophagosomes with lysosomes and producing stable nanodot-coated autophagosomes in tumours.
View Article and Find Full Text PDFEBioMedicine
January 2025
Biomedical Big Data Center, The First Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang, China. Electronic address:
Background: Coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2 virus infection, is characterized as a multisystem disease, potentially yielding multifaceted consequences on various organs at multiple levels. At the end of 2022, over 90% of the Chinese population was infected by SARS-CoV-2 within 35 days because of adjustments to epidemic prevention and control policies. This short-term change provides an unprecedented opportunity for comparative studies on COVID-19 infection among large populations.
View Article and Find Full Text PDFMar Pollut Bull
January 2025
University of Victoria, 3800 Finnerty Road, Victoria, BC V8W 2Y2, Canada. Electronic address:
Marine pollution poses significant risks to both marine ecosystems and human health, requiring effective monitoring and control measures. This study presents the Ocean Pollution Monitoring System (OPMS), a web application designed to visualize the seasonal and annual fluctuations of marine pollutants along coastal regions in Canada. The pollutants include fecal coliform and biotoxins such as paralytic shellfish poisoning (PSP), and amnesic shellfish poisoning (ASP).
View Article and Find Full Text PDFWomen Birth
January 2025
School of Nursing, Midwifery and Social Work, The University of Queensland, Whitty Building, Mater Hospital Campus, South Brisbane, Australia. Electronic address:
Background: Despite breastfeeding being widely accepted as the optimal feeding method for infants many women do not meet their breastfeeding goals or continue to breastfeed as long as recommended. Continuation of exclusive breastfeeding is multifactorial, with midwifery support during the postnatal period considered to be an important component. However, little is known about how women receive this support from midwives across varying models of care.
View Article and Find Full Text PDFCureus
December 2024
Anesthesiology, Vardhman Mahavir Medical College and Safdarjung Hospital, Delhi, IND.
Introduction Effective postoperative analgesia following lower segment cesarean section (LSCS) is crucial for promoting surgical recovery and fostering maternal-neonatal bonding. This study aimed to compare the efficacy of two IV dexamethasone doses (8 mg and 4 mg) in managing postoperative pain in LSCS patients. The objective was to assess whether the 4 mg dose provides comparable pain relief to the 8 mg dose, with the goal of identifying the optimal dosage for effective pain management with minimal side effects.
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