This study provides a detailed exposition of in-hospital community-acquired methicillin-resistant (CA-MRSA) which is a new strain of MRSA, and hospital-acquired methicillin-resistant (HA-MRSA) employing Caputo fractional operator. These two strains of MRSA, referred to as staph, have been a serious problem in hospitals and it is known that they give rise to more deaths per year than AIDS. Hence, the transmission dynamics determining whether the CA-MRSA overtakes HA-MRSA is analyzed by means of a non-local fractional derivative. We show the existence and uniqueness of the solutions of the fractional staph infection model through fixed-point theorems. Moreover, stability analysis and iterative solutions are furnished by the recursive procedure. We make use of the parameter values obtained from the Beth Israel Deaconess Medical Center. Analysis of the model under investigation shows that the disease-free equilibrium existing for all parameters is globally asymptotically stable when both and are less than one. We also carry out the sensitivity analysis to identify the most sensitive parameters for controlling the spread of the infection. Additionally, the solution for the above-mentioned model is obtained by the Laplace-Adomian decomposition method and various simulations are performed by using convenient fractional-order .
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http://dx.doi.org/10.1007/s12190-021-01502-3 | DOI Listing |
Water Res
January 2025
State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco- Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
The flow through the grit chamber is non-biochemically treated wastewater, which contains microorganisms mainly from the source of wastewater generation. There are limited reports on aerosol particles generated by grit chambers compared with those produced by biochemical treatment tanks. This study analyzed the fugitive characteristics of aerosol particles produced in grit chambers at nine wastewater treatment plants in three regions of China.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Division of Clinical Pathology, Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Background: Sepsis, a critical global health challenge, accounted for approximately 20% of worldwide deaths in 2017. Although the Sequential Organ Failure Assessment (SOFA) score standardizes the diagnosis of organ dysfunction, early sepsis detection remains challenging due to its insidious symptoms. Current diagnostic methods, including clinical assessments and laboratory tests, frequently lack the speed and specificity needed for timely intervention, particularly in vulnerable populations such as older adults, intensive care unit (ICU) patients, and those with compromised immune systems.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Internal Medicine, Faculty of Medicine, Gulu University, Gulu, Uganda.
Background: Cervical cancer screening program in Uganda is opportunistic and focuses mainly on women aged 25-49 years. Female sex workers (FSWs) are at increased risk of developing invasive cervical cancer. There is limited data regarding the uptake and acceptability of cervical cancer screening among FSWs in Uganda.
View Article and Find Full Text PDFPLoS One
January 2025
Université Paris Cité, IRD, MERIT, F-75006, Paris, France.
Introduction: Recently, efforts to eliminate malaria have shifted focus from symptomatic cases alone to include asymptomatic carriers, who are now recognized as significant contributors to the disease's transmission and control. This study examines the relationship between asymptomatic malaria infection and hemoglobin levels in Benin.
Methods: A cohort in Benin was enrolled and categorized into three age groups (under 5 years, 5-15 years, and over 15 years) for follow-up from August to November 2021.
PLoS One
January 2025
Department of Statistical Sciences, University of Cape Town, Cape Town, South Africa.
This study quantifies the impact of COVID-19 vaccination on hospitalization for COVID-19 infection in a South African private health insurance population. This retrospective cohort study is based on the analysis of demographic and claims records for 550,332 individuals belonging to two health insurance funds between 1 March 2020 and 31 December 2022. A Cox Proportional Hazards model was used to estimate the impact of vaccination (non-vaccinated, partly vaccinated, fully vaccinated) on COVID-19 hospitalization risk; and zero-inflated negative binomial models were used to estimate the impact of vaccination on hospital utilization and hospital expenditure for COVID-19 infection, with adjustments for age, sex, comorbidities and province of residence.
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