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Antithrombin III deficiency and idiopathic intracranial hypertension: a case report.
J Med Case Rep
January 2025
Headache Department, Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Background: Idiopathic intracranial hypertension (IIH) is a condition where the pressure of the cerebrospinal fluid in the brain increases without a known cause. It typically affects adults but can also occur in adolescents and children, although it is less common. Numerous elements, including coagulopathy, have been documented in previous cases as potential etiological factors of IIH.
View Article and Find Full Text PDFBilateral Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) Optic Neuritis: A Case Report.
Cureus
November 2024
Ophthalmology, International Islamic University Malaysia, Kuantan, MYS.
Article Synopsis
- Optic neuritis (ON) is an acquired disorder of the optic nerve linked with demyelinating conditions and can present differently in children compared to adults.
- The main concern for healthcare providers is the potential development of multiple sclerosis (MS) in patients with ON, which has led to a greater emphasis on distinguishing between MS and other demyelinating disorders like NMOSD and MOGAD.
- The paper discusses a case of a child with severe MOGAD ON, detailing the clinical features, investigations, and treatment that resulted in complete visual recovery.
Review of atypical optic neuritis.
Neurol Sci
December 2024
Institute of Medical Biochemistry, Scientific Research Department, University Clinical Center of Serbia, Belgrade, 11000, Serbia.
Optic neuritis (ON), an inflammatory optic neuropathy, is among the most common causes of visual loss. In its initial clinical appearance, ON may have unilateral or bilateral presentation, and anterior (papillitis) or retrobulbar localization. Traditionally, cases are divided into typical and atypical ON.
View Article and Find Full Text PDFHigh-altitude retinopathy and retinal hemorrhage: A case report.
Medicine (Baltimore)
November 2024
Department of Ophthalmology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Article Synopsis
- High-altitude retinopathy (HAR) is a vision-threatening condition caused by low oxygen levels at high altitudes, which may sometimes resolve on its own without symptoms.
- A 41-year-old man experienced vision loss after rapidly ascending to high altitude, leading to diagnoses of HAR following thorough ophthalmic evaluations revealing serious eye issues.
- Treatment included injections and medications to enhance eye health, and after 4 months, he showed improvement, emphasizing the importance of leaving high altitudes promptly to prevent long-term vision damage.
Case Report: IVIG causing bilateral papilledema and increased intracranial hypertension in patients with anti-TIF-1γ antibody-positive JDM.
Front Pediatr
November 2024
Department of Pediatrics, Golisano Children's Hospital, University of Rochester, Rochester, NY, United States.
Juvenile dermatomyositis is a systemic autoimmune disease characterized by progressive proximal muscle weakness, pathognomonic rashes, and often the presence of myositis-specific antibodies. Consensus treatment plans for pediatric patients with juvenile dermatomyositis recommend steroids and methotrexate as initial therapy. Patients with anti-transcription intermediary factor 1 gamma (anti-TIF-1γ) antibodies tend to have more refractory disease requiring more aggressive treatment with intravenous immunoglobulin, which is typically well tolerated.
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