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POLYPHARMACY AND CANCER: А NEW VISION FOR SKIN CANCER PATHOGENESIS-PHOTOTOXICITY AND PHOTOCARCINOGENICITY DUE TO NITROSAMINE CONTAMINATION DURING TELMISARTAN/ TAMSULOSIN INTAKE.
Georgian Med News
November 2024
4Department of Pathology, University of Virginia, Charlottesville, USA.
The toxicokinetics of nitrosamines remain a mystery to this day, though it appears that the role of nitrosamines in potentiating the generation of mutations required for the onset of skin cancer continues to be a significant concern. Nitrosamines are mutagens, genotoxic substances, and mediators of phototoxicity/carcinogenicity, whose long-term daily usage, in the context of polypharmacy, can result in the parallel appearance of heterogeneous forms of skin cancer: keratinocytic and melanocytic. But a number of clinical observations suggest that it is the nitrosamines that potentiate the multiple occurrences of skin cancer over the years, or recurrences of skin cancer localized in areas exposed to solar radiation.
View Article and Find Full Text PDFDo mothers' socioeconomic factors affect children's sodium and potassium intake?
Hypertens Res
January 2025
Department of Preventive Medicine and Public Health, Keio University School of Medicine, Tokyo, Japan.
A snapshot of cancer in Chile II: an update on research, strategies and analytical frameworks for equity, innovation and national development.
Biol Res
December 2024
Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Alameda 340, 8331150, Santiago, Chile.
Introduction: Chile has achieved developed nation status and boasts a life expectancy of 81 + years; however, the healthcare and research systems are unprepared for the social and economic burden of cancer. One decade ago, the authors put forward a comprehensive analysis of cancer infrastructure, together with a series of suggestions on research orientated political policy.
Objectives: Provide an update and comment on policy, infrastructure, gender equality, stakeholder participation and new challenges in national oncology.
Comment on "Total Magnesium Intake and Risk of Frailty in Older Women" by Struijk et al.-The Authors' Reply.
J Cachexia Sarcopenia Muscle
February 2025
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid-IdiPaz, Madrid, Spain.
Trends and hotspots in research on osteoporosis and nutrition from 2004 to 2024: a bibliometric analysis.
J Health Popul Nutr
November 2024
School of Nursing, Xi 'an Jiaotong University Health Science Center, Xi 'an, 710061, China.
Article Synopsis
- The study highlights the growing interest in the relationship between nutrition and osteoporosis, noting a surge in relevant articles published over the past two decades but a lack of comprehensive reviews in the field.
- Using bibliometric methods, the research analyzed 2138 articles from 2004 to 2024, finding that the U.S. leads in publication volume and identifying significant research topics like bone density and vitamin D.
- The authors suggest future studies focus on improving bone density measurement techniques, understanding fracture risk indicators, and examining the deeper connections between various nutrients and osteoporosis.
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