To evaluate the short-term effect of left subclavian artery (LSA) reconstruction with pre fenestration and external branch thoracic endovascular aortic repair (TEVAR) in the treatment of aortic arch descending lesions. The clinical data of 79 patients with aortic diseases who received LSA reconstruction in Tianjin Medical University General Hospital from November 2015 to October 2019 were analyzed retrospectively. According to different LSA reconstruction methods, they were divided into the fenestrated group (group f) 50 cases and the external branched group (group b) 29 cases. The surgical success rate, intraoperative and postoperative complication rate, re-intervention rate, mortality rate, and the change of the true and false lumen area of the dissection were compared and analyzed. There were no significant differences in the perioperative and recent total complication rate, secondary intervention rate and mortality between the two groups (0, 1.246, 0.156, all 0.05). The operation time of group f [(123.0±40.7 min)] was significantly longer than that of group b ((84.2±16.3) min, =2.173, 0.034). The degree of false lumen thrombosis of the stent segment was better than that of the non-stent segment (7.213, 14.359, both 0.05) in the two groups after surgery, but no significant difference between the two groups (1.510, 0.886, both 0.05). There was no significant difference in the change rate of the true and false lumen on each plane of the dissection between the two groups (all 0.05). Both fenestrated and external branched TEVAR reconstruction LSA have good safety and effectiveness in treating aortic arch descending lesions. The external branched TEVAR takes less time, has higher effectiveness for lesions with shorter landing zone, and has better aortic remodeling effect in the stent segment soon; and the fenestrated TEVAR has better economy.

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.cn112137-20200715-02128DOI Listing

Publication Analysis

Top Keywords

external branched
16
lsa reconstruction
12
false lumen
12
pre fenestration
8
fenestration external
8
thoracic endovascular
8
endovascular aortic
8
aortic repair
8
aortic arch
8
arch descending
8

Similar Publications

Bayesian efficient safety monitoring: a simple and well-performing framework to continuous safety monitoring of adverse events in randomized clinical trials.

J Biopharm Stat

January 2025

Johnson and Johnson Limited, Statistical Modeling and Methodology, Statistical Decision Sciences, Raritan, USA.

During randomized controlled trials, it is critical to remain vigilant in safety monitoring. A common approach is to present information over time, such as frequency tables and graphs, when analyzing adverse events. Nevertheless, there is still a need for developing statistical methods for analyzing safety data of a dynamic nature.

View Article and Find Full Text PDF

Objectives: To develop a machine learning-based prediction model using clinical data from the first 24 h of ICU admission to enable rapid screening and early intervention for sepsis patients.

Methods: This multicenter retrospective cohort study analyzed electronic medical records of sepsis patients using machine learning methods. We evaluated model performance in predicting sepsis outcomes within the first 24 h of ICU admission across US and Chinese healthcare settings.

View Article and Find Full Text PDF

Detecting the saddling deformations in nickel meso-phenyl substituted porphyrins using low-frequency Raman characteristic peaks.

Spectrochim Acta A Mol Biomol Spectrosc

January 2025

Institute of Intelligent Machines, Hefei Institute of Intelligent Agriculture, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China; Science Island Branch of Graduate School, University of Science & Technology of China, Hefei 230026, China. Electronic address:

The out-of-plane (OOP) deformations of metalloporphyrins macrocycle are closely related to their biological functions, and Raman spectroscopy is a powerful tool for investigating OOP deformations. However, due to the interplay of electronic structure, substituents, porphyrin macrocycle in-plane (IP) and OOP deformations, it is challenging to measure the OOP deformations directly, or, establish a confirmative correlation between the frequency shifts of characteristic peaks and specific OOP deformation changes. In this work, we first selected the model porphyrin Ni-P and employed DFT calculations to explore the relationship between the ruffling and saddling deformation changes and their corresponding Raman spectral differences.

View Article and Find Full Text PDF

A dendritic hexamer acceptor enables 19.4% efficiency with exceptional stability in organic solar cells.

Nat Commun

January 2025

Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, China.

To achieve the commercialization of organic solar cells (OSCs), it is crucial not only to enhance power conversion efficiency (PCE) but also to improve device stability through rational molecular design. Recently emerging giant molecular acceptor (GMA) materials offer various advantages, such as precise chemical structure, high molecular weight (beneficial to film stability under several external stress), and impressive device efficiency, making them a promising candidate. Here, we report a dendritic hexamer acceptor developed through a branch-connecting strategy, which overcomes the molecular weight bottleneck of GMAs and achieves a high production yield over 58%.

View Article and Find Full Text PDF

Background: Oculodentodigital dysplasia (ODDD) is a rare syndrome that causes a constellation of facial, ophthalmic, dental, and limb abnormalities. Variants in the gap junction alpha-1 () gene have been described in patients with ODDD. Hereby we present the ocular manifestations in a patient with recessive ODDD due to a novel homozygous frameshift variant in .

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!