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A time series study of the association between extreme temperature and ozone on varicella incidence.
Sci Rep
December 2024
Department of Epidemiology and Statistics, School of Public Health, Hebei Province Key Laboratory of Environment and Human Health, Hebei Medical University, 361 Zhongshan East Road, Shijiiazhuang, 050017, China.
This study aimed to discuss the effects of extreme temperatures and ozone on the incidence of varicella in Shijiazhuang City from 2014 to 2022, which provides new ideas for preventing public health events. METHODS We collected varicella cases in Shijiazhuang, China, from 2014 to 2022 and evaluated the relationship between temperature extremes and ozone on varicella incidence by building distributional lag nonlinear models. The analysis was stratified by age and sex, with 19,188 varicella cases reported.
View Article and Find Full Text PDFAssociations of Serum Manganese, Zinc, Copper, and Selenium Concentrations With Autism Spectrum Disorders in Chinese Children: A Case-Control Study.
Autism Res
December 2024
School of Public Health, Hubei University of Medicine, Shiyan, China.
Imbalances in several trace elements related to antioxidant function may lead to autism spectrum disorder (ASD)-related physiological dysfunction. Nonetheless, contradictory results have been found on the connection between these elements and ASD, and studies of their joint effects and interactions have been insufficient. We therefore designed a case-control study of 152 ASD children and 152 age- and sex-matched typically developing (TD) children to explore the individual and combined associations of manganese (Mn), zinc (Zn), copper (Cu), and selenium (Se) with ASD.
View Article and Find Full Text PDFLiver Function Biomarkers and Lung Cancer Risk: A Prospective Cohort Study in the UK Biobank.
Clin Respir J
December 2024
Department of Radiation Oncology, Yunfu People's Hospital, Yunfu, China.
Background: As the primary organ of metabolism and detoxification, the liver may contribute to the pathogenesis of lung cancer. We aimed to illuminate the intricate link between liver function biomarkers and lung cancer risk, as well as delineate the role of smoking behavior within this association.
Methods: We investigated the associations of seven liver function biomarkers levels (alkaline phosphatase [ALP], alanine transaminase [ALT], total bilirubin [TBIL], albumin [ALB], gamma-glutamyltransferase [GGT], aspartate transaminase [AST], and total protein [TP]) with lung cancer risk across the UK Biobank (N = 337 499) through restricted cubic splines and Cox proportional hazards models.
The prognostic value of the systemic immunity-inflammation index for cardiovascular and all-cause mortality in cardiovascular disease patients with diabetes or prediabetes.
J Diabetes Investig
December 2024
Key Laboratory Diseases Immunology, Department of Metabolism and Endocrinology, National Clinical Research Center for Metabolic Diseases, Ministry of Education, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Background: The relationship between the systemic immune-inflammatory index (SII) and the prognosis of cardiovascular disease (CVD) patients with diabetes or prediabetes remains uncertain. This study investigated the association between baseline SII and all-cause and cardiovascular mortality in American adults with CVD and diabetes or prediabetes.
Methods: Our survey included 4,060 adults with cardiovascular disease and diabetes or prediabetes from the National Health and Nutrition Examination Survey (1998-2020).
Developing and Externally Validating a Simple Index Based on the Nonlinear Relationship of Fecal Calprotectin and Long-Term Outcomes in Ulcerative Colitis.
J Inflamm Res
December 2024
Department of Gastroenterology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People's Republic of China.
Background: The possible nonlinear association with therapeutic outcomes in ulcerative colitis may contribute to the inconclusive cutoff values of fecal calprotectin (FC). We aimed to explore the nonlinear association between FC levels and long-term therapeutic outcomes in patients with ulcerative colitis and establish a clinically applicable FC index.
Methods: We included patients treated with vedolizumab or adalimumab from the VARSITY (n=661) and GEMINI 1 (n=620) studies as discovery and validation cohorts, respectively.
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