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HPV-16-associated lymphoepithelial-like carcinoma mimicking rectal tonsil. | LitMetric

HPV-16-associated lymphoepithelial-like carcinoma mimicking rectal tonsil.

Clin J Gastroenterol

Division of Hematology and Oncology, Department of Internal Medicine, University of Florida College of Medicine, Shands Hospital, 1600 SW Archer Road, Gainesville, FL, 32610, USA.

Published: June 2021

Lymphoepithelial-like carcinoma is a rare malignancy characterized by lack of cellular differentiation and associated nonneoplastic lymphoplasmacytic cell infiltrate that is rarely seen in the colon. Although many cases are associated with EBV infection, HPV may be present in LELC arising in sites known for HPV-driven malignancies, like the anogenital region. We report a case of lymphoepithelial-like carcinoma mimicking a rectal tonsil in a 51-year-old female. Attentive evaluation must be taken to identify this tumor in locations where prominent lymphoid stroma is an expected finding.

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http://dx.doi.org/10.1007/s12328-021-01362-1DOI Listing

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